Azide-alkyne cycloadditions in a vortex fluidic device: Enhanced "on water" effects and catalysis in flow

The Vortex Fluidic Device is a flow reactor that processes reactions in thin films. Running the metal-free azide-alkyne cycloaddition in this reactor revealed a dramatic enhancement of the "on water"effect. For the copper-catalyzed azide-alkyne cycloaddition, stainless steel or copper jet...

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Detalles Bibliográficos
Autores: Oksdath Mansilla, Gabriela, Kucera, Renata L., Chalker, Justin Mark, Raston, Colin Llewellyn
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/172505
Acceso en línea:http://hdl.handle.net/11336/172505
Access Level:acceso abierto
Palabra clave:On-water effect
Vortex fluidic device
Flow chemistry
Click chemistry
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:The Vortex Fluidic Device is a flow reactor that processes reactions in thin films. Running the metal-free azide-alkyne cycloaddition in this reactor revealed a dramatic enhancement of the "on water"effect. For the copper-catalyzed azide-alkyne cycloaddition, stainless steel or copper jet feeds were effective reservoirs of active copper catalyst.