Existence and multiplicity of periodic solutions for a generalized hematopoiesis model

A generalization of the nonautonomous Mackey–Glass equation for the regulation of the hematopoiesis with several non-constant delays is studied. Using topological degree methods we prove, under appropriate conditions, the existence of multiple positive periodic solutions. Moreover, we show that the...

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Detalles Bibliográficos
Autores: Amster, Pablo Gustavo, Balderrama, Rocio Celeste
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/55575
Acceso en línea:http://hdl.handle.net/11336/55575
Access Level:acceso abierto
Palabra clave:DEGREE THEORY
GLOBAL ATTRACTOR
HEMATOPOIESIS
MULTIPLICITY
NONLINEAR NONAUTONOMOUS DELAY DIFFERENTIAL EQUATIONS
POSITIVE PERIODIC SOLUTIONS
https://purl.org/becyt/ford/1.1
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/1.6
Descripción
Sumario:A generalization of the nonautonomous Mackey–Glass equation for the regulation of the hematopoiesis with several non-constant delays is studied. Using topological degree methods we prove, under appropriate conditions, the existence of multiple positive periodic solutions. Moreover, we show that the conditions are necessary, in the sense that if some sort of complementary conditions are assumed then the trivial equilibrium is a global attractor for the positive solutions and hence periodic solutions do not exist.