Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process

Acylglycerides are esters formed from glycerol and fatty acids. The structure of these glycerides affects their digestion and absorption. In this work, the synthesis of acylglycerides with high nutritional value by an enzymatic process in two stages is presented. In the first stage, the esterificati...

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Detalles Bibliográficos
Autores: Sanchez, Daniel Alberto, Tonetto, Gabriela Marta, Ferreira, María Luján
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/157667
Acceso en línea:http://hdl.handle.net/11336/157667
Access Level:acceso abierto
Palabra clave:NUTRITIONAL ACYLGLYCERIDES
ENZYMATIC SYNTHESIS
LIPASES
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
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spelling Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step processSanchez, Daniel AlbertoTonetto, Gabriela MartaFerreira, María LujánNUTRITIONAL ACYLGLYCERIDESENZYMATIC SYNTHESISLIPASEShttps://purl.org/becyt/ford/2.9https://purl.org/becyt/ford/2Acylglycerides are esters formed from glycerol and fatty acids. The structure of these glycerides affects their digestion and absorption. In this work, the synthesis of acylglycerides with high nutritional value by an enzymatic process in two stages is presented. In the first stage, the esterification of glycerol and capric acid catalyzed by Lipozyme RM IM was carried out. In this reaction, 73% conversion of capric acid and 71% selectivity to 1,3-dicaprin was achieved. The diglyceride was separated and purified efficiently by a simple liquid-liquid extraction procedure. The dicaprin was esterified with palmitic acid using Burkholderia cepacia lipase immobilized on chitosan as the catalyst. In this second stage conversions of 1,3-dicaprin with values between 48 and 87% and with high selectivity towards the esterification of the sn-2 position were achieved. The reaction product had between 76 and 90% of acylglycerides with high nutritional value, depending on the reaction conditions.Fil: Sanchez, Daniel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur. Departamento de Ingeniería Química; ArgentinaFil: Tonetto, Gabriela Marta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur. Departamento de Ingeniería Química; ArgentinaFil: Ferreira, María Luján. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur. Departamento de Química; ArgentinaPlanta Piloto de Ingeniería Química2019-08-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/157667Sanchez, Daniel Alberto; Tonetto, Gabriela Marta; Ferreira, María Luján; Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process; Planta Piloto de Ingeniería Química; Latin American Applied Research; 49; 2; 28-8-2019; 137-1420327-07931851-8796CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://laar.plapiqui.edu.ar/OJS/index.php/laar/article/view/38info:eu-repo/semantics/altIdentifier/doi/10.52292/j.laar.2019.38info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T14:13:33Zoai:ri.conicet.gov.ar:11336/157667instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 14:13:34.183CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process
title Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process
spellingShingle Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process
Sanchez, Daniel Alberto
NUTRITIONAL ACYLGLYCERIDES
ENZYMATIC SYNTHESIS
LIPASES
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
title_short Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process
title_full Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process
title_fullStr Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process
title_full_unstemmed Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process
title_sort Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process
dc.creator.none.fl_str_mv Sanchez, Daniel Alberto
Tonetto, Gabriela Marta
Ferreira, María Luján
author Sanchez, Daniel Alberto
author_facet Sanchez, Daniel Alberto
Tonetto, Gabriela Marta
Ferreira, María Luján
author_role author
author2 Tonetto, Gabriela Marta
Ferreira, María Luján
author2_role author
author
dc.subject.none.fl_str_mv NUTRITIONAL ACYLGLYCERIDES
ENZYMATIC SYNTHESIS
LIPASES
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
topic NUTRITIONAL ACYLGLYCERIDES
ENZYMATIC SYNTHESIS
LIPASES
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
description Acylglycerides are esters formed from glycerol and fatty acids. The structure of these glycerides affects their digestion and absorption. In this work, the synthesis of acylglycerides with high nutritional value by an enzymatic process in two stages is presented. In the first stage, the esterification of glycerol and capric acid catalyzed by Lipozyme RM IM was carried out. In this reaction, 73% conversion of capric acid and 71% selectivity to 1,3-dicaprin was achieved. The diglyceride was separated and purified efficiently by a simple liquid-liquid extraction procedure. The dicaprin was esterified with palmitic acid using Burkholderia cepacia lipase immobilized on chitosan as the catalyst. In this second stage conversions of 1,3-dicaprin with values between 48 and 87% and with high selectivity towards the esterification of the sn-2 position were achieved. The reaction product had between 76 and 90% of acylglycerides with high nutritional value, depending on the reaction conditions.
publishDate 2019
dc.date.none.fl_str_mv 2019-08-28
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/157667
Sanchez, Daniel Alberto; Tonetto, Gabriela Marta; Ferreira, María Luján; Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process; Planta Piloto de Ingeniería Química; Latin American Applied Research; 49; 2; 28-8-2019; 137-142
0327-0793
1851-8796
CONICET Digital
CONICET
url http://hdl.handle.net/11336/157667
identifier_str_mv Sanchez, Daniel Alberto; Tonetto, Gabriela Marta; Ferreira, María Luján; Synthesis of Acilglycerides with high nutritional value by an enzymatic two-step process; Planta Piloto de Ingeniería Química; Latin American Applied Research; 49; 2; 28-8-2019; 137-142
0327-0793
1851-8796
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://laar.plapiqui.edu.ar/OJS/index.php/laar/article/view/38
info:eu-repo/semantics/altIdentifier/doi/10.52292/j.laar.2019.38
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Planta Piloto de Ingeniería Química
publisher.none.fl_str_mv Planta Piloto de Ingeniería Química
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 15.811543

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