Cationic cellulose and its interaction with chondroitin sulfate: rheological properties of the polyelectrolyte complex

This work describes the polyelectrolyte complexation between polyquaternium cellulose (PQ-10) and chondroitin 4-sulfate (C-4S), an important structural component of cartilages. The complex shows different behaviors with increasing concentrations of the polyanion. Initially, PQ-10/C-4S interaction fo...

Descripción completa

Detalles Bibliográficos
Autores: Bierbrauer, Karina Lilian, Alasino, Roxana Valeria, Strumia, Miriam Cristina, Beltramo, Dante Miguel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/13680
Acceso en línea:http://hdl.handle.net/11336/13680
Access Level:acceso abierto
Palabra clave:Polyquaternium
Chondroitin Sulfate
Alginate
Carrageenan
Electrostatic Interactions
Rheology
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:This work describes the polyelectrolyte complexation between polyquaternium cellulose (PQ-10) and chondroitin 4-sulfate (C-4S), an important structural component of cartilages. The complex shows different behaviors with increasing concentrations of the polyanion. Initially, PQ-10/C-4S interaction forms a soluble, translucent hydrogel that reaches maximum viscosity at a sulfate carboxylate/quaternary ammonium molar ratio lower than 1. After that, the complex begins to aggregate until complete precipitation, and finally, at higher concentrations of C-4S, the resuspension of the aggregate is observed. Further addition of PQ-10 initiates new cycles of precipitation/resuspension for at least seven times. C-4S contains sulfates and carboxylates able to interact with quaternary ammonium of PQ-10. The results of a comparative study with polymers containing only carboxylate or sulfate to evaluate the influence of each group suggest that the phenomena observed involved, essentially, carboxylate groups.