Citotoxicidad de Hidroxiapatita y su morfología en composites con Ti

Hydroxyapatite (Ca10(PO4)6(OH)2 is the material used to improve osseointegration of implants in humans. Traditionally Ti-based implant is coated with hydroxyapatite, but this presents several problems such as, low fracture toughness of hydroxyapatite, generation of interfacial cracks during the depo...

Descripción completa

Detalles Bibliográficos
Autores: Comin, Romina, Reyna Musso, Laura A., Cid, Mariana Paula, Oldani, Carlos Rodolfo, Salvatierra, Nancy Alicia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:español
OAI Identifier:oai:ri.conicet.gov.ar:11336/76806
Acceso en línea:http://hdl.handle.net/11336/76806
Access Level:acceso abierto
Palabra clave:Composite
Pulvimetalurgia
Hidroxiapatita
Biocompatibilidad
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
Descripción
Sumario:Hydroxyapatite (Ca10(PO4)6(OH)2 is the material used to improve osseointegration of implants in humans. Traditionally Ti-based implant is coated with hydroxyapatite, but this presents several problems such as, low fracture toughness of hydroxyapatite, generation of interfacial cracks during the deposition step and low adhesion ceramic /metal. Furthermore some studies reported that some excellent Ti-HA bio-composites could be fabricated by the powder metallurgy (PM) technology. In present study it was investigate the cytotoxicity of coralline and bovine hydroxyapatite. Topography of Ti-HA composites obtained by powder metallurgy was evaluated by scanning electron microscopy. The results showed that HA samples analyzed did not affect cell viability. Furthermore, a good integration of HA to the matrix of Ti was observed by microscopy studies