Polymeric Hydrogels as Technology Platform for Drug Delivery Applications

Hydrogels have become key players in the field of drug delivery owing to their great versatility in terms of composition and adjustability to various administration routes, from parenteral (e.g., intravenous) to non-parenteral (e.g., oral, topical) ones. In addition, based on the envisioned applicat...

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Detalhes bibliográficos
Autores: Sosnik, Alejandro Dario, Seremeta, Katia Pamela
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/41070
Acesso em linha:http://hdl.handle.net/11336/41070
Access Level:acceso abierto
Palavra-chave:POLYMERIC HYDROGELS
DRUG DELIVERY
ADMINISTRATION ROUTES
MUCOSAL ROUTES
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
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spelling Polymeric Hydrogels as Technology Platform for Drug Delivery ApplicationsSosnik, Alejandro DarioSeremeta, Katia PamelaPOLYMERIC HYDROGELSDRUG DELIVERYADMINISTRATION ROUTESMUCOSAL ROUTEShttps://purl.org/becyt/ford/2.5https://purl.org/becyt/ford/2Hydrogels have become key players in the field of drug delivery owing to their great versatility in terms of composition and adjustability to various administration routes, from parenteral (e.g., intravenous) to non-parenteral (e.g., oral, topical) ones. In addition, based on the envisioned application, the design of bioadhesive or mucoadhesive hydrogels with prolonged residence time in the administration site may be beneficial. For example, hydrogels are used as wound dressings and patches for local and systemic therapy. In a similar way, they can be applied in the vaginal tract for local treatment or in the nasal cavity for a similar goal or, conversely, to target the central nervous system by the nose-to-brain pathway. Overall, hydrogels have demonstrated outstanding capabilities to ensure patient compliance, while achieving long-term therapeutic effects. The present work overviews the most relevant and recent applications of hydrogels in drug delivery with special emphasis on mucosal routes.Fil: Sosnik, Alejandro Dario. Technion - Israel Institute of Technology; IsraelFil: Seremeta, Katia Pamela. Universidad Nacional del Chaco Austral. Departamento de Ciencias Básicas y Aplicadas. Laboratorio de Ingeniería de las Reacciones Químicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaMultidisciplinary Digital Publishing Institute2017-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/41070Sosnik, Alejandro Dario; Seremeta, Katia Pamela; Polymeric Hydrogels as Technology Platform for Drug Delivery Applications; Multidisciplinary Digital Publishing Institute; Gels; 3; 3; 7-2017; 1-222310-2861CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.mdpi.com/2310-2861/3/3/25info:eu-repo/semantics/altIdentifier/doi/10.3390/gels3030025info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:43:36Zoai:ri.conicet.gov.ar:11336/41070instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:43:36.292CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Polymeric Hydrogels as Technology Platform for Drug Delivery Applications
title Polymeric Hydrogels as Technology Platform for Drug Delivery Applications
spellingShingle Polymeric Hydrogels as Technology Platform for Drug Delivery Applications
Sosnik, Alejandro Dario
POLYMERIC HYDROGELS
DRUG DELIVERY
ADMINISTRATION ROUTES
MUCOSAL ROUTES
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
title_short Polymeric Hydrogels as Technology Platform for Drug Delivery Applications
title_full Polymeric Hydrogels as Technology Platform for Drug Delivery Applications
title_fullStr Polymeric Hydrogels as Technology Platform for Drug Delivery Applications
title_full_unstemmed Polymeric Hydrogels as Technology Platform for Drug Delivery Applications
title_sort Polymeric Hydrogels as Technology Platform for Drug Delivery Applications
dc.creator.none.fl_str_mv Sosnik, Alejandro Dario
Seremeta, Katia Pamela
author Sosnik, Alejandro Dario
author_facet Sosnik, Alejandro Dario
Seremeta, Katia Pamela
author_role author
author2 Seremeta, Katia Pamela
author2_role author
dc.subject.none.fl_str_mv POLYMERIC HYDROGELS
DRUG DELIVERY
ADMINISTRATION ROUTES
MUCOSAL ROUTES
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
topic POLYMERIC HYDROGELS
DRUG DELIVERY
ADMINISTRATION ROUTES
MUCOSAL ROUTES
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
description Hydrogels have become key players in the field of drug delivery owing to their great versatility in terms of composition and adjustability to various administration routes, from parenteral (e.g., intravenous) to non-parenteral (e.g., oral, topical) ones. In addition, based on the envisioned application, the design of bioadhesive or mucoadhesive hydrogels with prolonged residence time in the administration site may be beneficial. For example, hydrogels are used as wound dressings and patches for local and systemic therapy. In a similar way, they can be applied in the vaginal tract for local treatment or in the nasal cavity for a similar goal or, conversely, to target the central nervous system by the nose-to-brain pathway. Overall, hydrogels have demonstrated outstanding capabilities to ensure patient compliance, while achieving long-term therapeutic effects. The present work overviews the most relevant and recent applications of hydrogels in drug delivery with special emphasis on mucosal routes.
publishDate 2017
dc.date.none.fl_str_mv 2017-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/41070
Sosnik, Alejandro Dario; Seremeta, Katia Pamela; Polymeric Hydrogels as Technology Platform for Drug Delivery Applications; Multidisciplinary Digital Publishing Institute; Gels; 3; 3; 7-2017; 1-22
2310-2861
CONICET Digital
CONICET
url http://hdl.handle.net/11336/41070
identifier_str_mv Sosnik, Alejandro Dario; Seremeta, Katia Pamela; Polymeric Hydrogels as Technology Platform for Drug Delivery Applications; Multidisciplinary Digital Publishing Institute; Gels; 3; 3; 7-2017; 1-22
2310-2861
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.mdpi.com/2310-2861/3/3/25
info:eu-repo/semantics/altIdentifier/doi/10.3390/gels3030025
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 15.811543

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