Redox regulation of inflammatory processes
Oxidative stress mediators such as Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) can be considered double edge molecules, whenever their role in inflammatory pathways is considered. Indeed, if on one hand ROS/RNS are important inflammatory effectors involved in the invading patho...
| Autores: | , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2016 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/47357 |
| Acceso en línea: | http://hdl.handle.net/11336/47357 |
| Access Level: | acceso abierto |
| Palabra clave: | Oxidative Stress Inflammation Redox Signaling Reactive Oxygen Species https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
| Sumario: | Oxidative stress mediators such as Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) can be considered double edge molecules, whenever their role in inflammatory pathways is considered. Indeed, if on one hand ROS/RNS are important inflammatory effectors involved in the invading pathogens clearance and resolving the damage and inducing tissue repair; on the other hand, ROS/RNS can also be inflammatory initiators as a consequence of oxidizing biomolecules such as lipids, proteins and DNA, leading to tissue damage and switching acute to chronic inflammation. |
|---|