Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas
1-(Acyl/aroyl)-3-(substituted)thioureas are privileged architectures that have received remarkable attention of researchers in view of their variable topological aspects, binding modes and broad spectrum promising pharmacological properties. Reactivity of acyl thiourea derivatives has presented vari...
| Autores: | , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2016 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/48437 |
| Acceso en línea: | http://hdl.handle.net/11336/48437 |
| Access Level: | acceso abierto |
| Palabra clave: | Acyl Thiourea Corrosion Electronics Ion Sensors Medicinal https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
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Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureasSaeed, AamerQamar, RabiaFattah, Tanzeela AbdulFlörke, UlrichErben, Mauricio FedericoAcyl ThioureaCorrosionElectronicsIon SensorsMedicinalhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/11-(Acyl/aroyl)-3-(substituted)thioureas are privileged architectures that have received remarkable attention of researchers in view of their variable topological aspects, binding modes and broad spectrum promising pharmacological properties. Reactivity of acyl thiourea derivatives has presented various organic transformations into other demanding scaffolds and this is an attractive strategy for synthetic chemists to access heterocyclic cores. Multiple binding sites make them flexible ligands for complexation with transition metals thus occupying a distinct position in coordination chemistry. 1-(Acyl/aroyl)-3-(substituted)thioureas have also emerged as attractive candidates in various fields such as ion sensors, corrosion inhibitors, molecular electronics, in metal extraction and in pharmaceuticals. The medicinal chemistry of this organo-sulfur framework and the derived metal complexes has witnessed fantastic progress in the current era. In continuation of our efforts to compile data on the structural aspects and numerous applications of 1-(acyl/aroyl)-3-(substituted)thiourea analogs, continuous advances have prompted us to present an overview of the last 2 years literature on this exciting family of compounds through this review article.Fil: Saeed, Aamer. Quaid-i-Azam University; PakistánFil: Qamar, Rabia. Quaid-i-Azam University; PakistánFil: Fattah, Tanzeela Abdul. Quaid-i-Azam University; PakistánFil: Flörke, Ulrich. Universität Paderborn; AlemaniaFil: Erben, Mauricio Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; ArgentinaSpringer2016-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/48437Saeed, Aamer; Qamar, Rabia; Fattah, Tanzeela Abdul; Flörke, Ulrich; Erben, Mauricio Federico; Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas; Springer; Research on Chemical Intermediates; 43; 5; 11-2016; 3053-30930922-61681568-5675CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1007/s11164-016-2811-5info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs11164-016-2811-5info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:38:04Zoai:ri.conicet.gov.ar:11336/48437instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:38:05.166CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas |
| title |
Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas |
| spellingShingle |
Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas Saeed, Aamer Acyl Thiourea Corrosion Electronics Ion Sensors Medicinal https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| title_short |
Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas |
| title_full |
Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas |
| title_fullStr |
Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas |
| title_full_unstemmed |
Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas |
| title_sort |
Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas |
| dc.creator.none.fl_str_mv |
Saeed, Aamer Qamar, Rabia Fattah, Tanzeela Abdul Flörke, Ulrich Erben, Mauricio Federico |
| author |
Saeed, Aamer |
| author_facet |
Saeed, Aamer Qamar, Rabia Fattah, Tanzeela Abdul Flörke, Ulrich Erben, Mauricio Federico |
| author_role |
author |
| author2 |
Qamar, Rabia Fattah, Tanzeela Abdul Flörke, Ulrich Erben, Mauricio Federico |
| author2_role |
author author author author |
| dc.subject.none.fl_str_mv |
Acyl Thiourea Corrosion Electronics Ion Sensors Medicinal https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| topic |
Acyl Thiourea Corrosion Electronics Ion Sensors Medicinal https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| description |
1-(Acyl/aroyl)-3-(substituted)thioureas are privileged architectures that have received remarkable attention of researchers in view of their variable topological aspects, binding modes and broad spectrum promising pharmacological properties. Reactivity of acyl thiourea derivatives has presented various organic transformations into other demanding scaffolds and this is an attractive strategy for synthetic chemists to access heterocyclic cores. Multiple binding sites make them flexible ligands for complexation with transition metals thus occupying a distinct position in coordination chemistry. 1-(Acyl/aroyl)-3-(substituted)thioureas have also emerged as attractive candidates in various fields such as ion sensors, corrosion inhibitors, molecular electronics, in metal extraction and in pharmaceuticals. The medicinal chemistry of this organo-sulfur framework and the derived metal complexes has witnessed fantastic progress in the current era. In continuation of our efforts to compile data on the structural aspects and numerous applications of 1-(acyl/aroyl)-3-(substituted)thiourea analogs, continuous advances have prompted us to present an overview of the last 2 years literature on this exciting family of compounds through this review article. |
| publishDate |
2016 |
| dc.date.none.fl_str_mv |
2016-11 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
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article |
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publishedVersion |
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http://hdl.handle.net/11336/48437 Saeed, Aamer; Qamar, Rabia; Fattah, Tanzeela Abdul; Flörke, Ulrich; Erben, Mauricio Federico; Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas; Springer; Research on Chemical Intermediates; 43; 5; 11-2016; 3053-3093 0922-6168 1568-5675 CONICET Digital CONICET |
| url |
http://hdl.handle.net/11336/48437 |
| identifier_str_mv |
Saeed, Aamer; Qamar, Rabia; Fattah, Tanzeela Abdul; Flörke, Ulrich; Erben, Mauricio Federico; Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas; Springer; Research on Chemical Intermediates; 43; 5; 11-2016; 3053-3093 0922-6168 1568-5675 CONICET Digital CONICET |
| dc.language.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1007/s11164-016-2811-5 info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs11164-016-2811-5 |
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info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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openAccess |
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https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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application/pdf application/pdf |
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Springer |
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Springer |
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reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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