Augmented serum levels of the IGF-I/IGFBP3 ratio in pre-menopausal patients with type I breast cysts

Gross cystic disease (GCD) is the most common benign breast pathology. Although breast cysts are not considered pre-malignant lesions, an increased risk of breast cancer has been reported for patients with type I cysts (Na(+)/K(+)<3). Furthermore, an augmented IGF-I/IGF-binding protein-3 (IGFBP-3...

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Detalles Bibliográficos
Autores: Enriori, Pablo J., Fischer, Carlos R., Gori, Jorge R., Etkin, Alberto E., Calandra, Ricardo Saul, Luthy, Isabel Alicia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/36233
Acceso en línea:http://hdl.handle.net/11336/36233
Access Level:acceso abierto
Palabra clave:Breast
Cyst Fluid
Igf-I
Igf-Bp-3
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/3.1
Descripción
Sumario:Gross cystic disease (GCD) is the most common benign breast pathology. Although breast cysts are not considered pre-malignant lesions, an increased risk of breast cancer has been reported for patients with type I cysts (Na(+)/K(+)<3). Furthermore, an augmented IGF-I/IGF-binding protein-3 (IGFBP-3) ratio has been described in breast cancer patients. The objective was to evaluate serum IGF-I and binding protein concentrations of type I and type II cyst patients as compared with healthy women.