Novel technique for ST-T interval characterization in patients with acute myocardial ischemia

Background The novel signal processing techniques have allowed and improved the use of vectorcardiography (VCG) to diagnose and characterize myocardial ischemia. Herein, we studied vectorcardiographic dynamic changes of ventricular repolarization in 80 patients before (control) and during Percutaneo...

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Detalhes bibliográficos
Autores: Correa, Raúl Julián, Arini, Pedro David, Correa, Lorena, Valentinuzzi, Max, Laciar Leber, Eric
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/12178
Acesso em linha:http://hdl.handle.net/11336/12178
Access Level:acceso abierto
Palavra-chave:St-T
Vcg
Ptca
Digital Signal Processing
https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
Descrição
Resumo:Background The novel signal processing techniques have allowed and improved the use of vectorcardiography (VCG) to diagnose and characterize myocardial ischemia. Herein, we studied vectorcardiographic dynamic changes of ventricular repolarization in 80 patients before (control) and during Percutaneous Transluminal Coronary Angioplasty (PTCA). Methods We propose four vectorcardiographic ST-T parameters, i.e., (a) ST Vector Magnitude Area (aSTVM); (b) T-wave Vector Magnitude Area (aTVM); (c) ST-T Vector Magnitude Difference (ST-TVD), and (d) T-wave Vector Magnitude Difference (TVD). For comparison, the conventional ST-Change Vector Magnitude (STCVM) and Spatial Ventricular Gradient (SVG) were also calculated. Results Our results indicate that several vectorcardiographic parameters show significant differences (p-value<0.05) before starting and during PTCA. Statistical minute-by-minute PTCA comparison against the control situation showed that ischemic monitoring reached a sensitivity=90.5% and a specificity=92.6% at the 5th minute of the PTCA, when aSTVM and ST-TVD were used as classifiers. Conclusions We conclude that the sensitivity and specificity for acute ischemia monitoring could be increased with the use of only two vectorcardiographic parameters. Hence, the proposed technique based on vectorcardiography could be used in addition to the conventional ST-T analysis for better monitoring of ischemic patients.