Editorial : Foot-and-mouth disease epidemiology, vaccines and vaccination : moving forward

Vaccination has played a major role in foot-and-mouth disease (FMD) control. There are different approaches to the design and implementation of vaccination campaigns, and epidemiological information is paramount in influencing the vaccine and vaccination strategy that best suit each geographic locat...

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Detalhes bibliográficos
Autores: Capozzo, Alejandra, Vosloo, Wilna, de los Santos, Teresa, Pérez, Andrés M., Perez Filgueira, Daniel Mariano
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Argentina
Recursos:Instituto Nacional de Tecnología Agropecuaria
Repositorio:INTA Digital (INTA)
Idioma:inglés
OAI Identifier:oai:localhost:20.500.12123/15223
Acesso em linha:http://hdl.handle.net/20.500.12123/15223
https://www.frontiersin.org/articles/10.3389/fvets.2023.1231005/full
https://doi.org/10.3389/fvets.2023.1231005
Access Level:acceso abierto
Palavra-chave:Foot-and-mouth Disease
Vaccines
Vaccination
Epidemiology
Fiebre Aftosa
Vacuna
Vacunación
Epidemiología
Efficacy Assessment
Evaluación de Eficacia
Descrição
Resumo:Vaccination has played a major role in foot-and-mouth disease (FMD) control. There are different approaches to the design and implementation of vaccination campaigns, and epidemiological information is paramount in influencing the vaccine and vaccination strategy that best suit each geographic location. FMD-endemic regions typically organize vaccination campaigns as a routine preventive control policy or to mitigate the impact of the disease. The majority of currently used vaccines are formulated with chemically inactivated whole-viral particles and suitable adjuvants such as single and double oil emulsions. The most recent strains circulating in a particular region are typically selected as antigens based on the results of vaccine-matching data and in vitro experiments, however, predictions based on vaccine-matching approaches are usually uncertain without a live virus challenge in natural hosts combined with reliable field data. Vaccine selection and successful vaccination campaigns rely on a deep knowledge of the epidemiology of the region where these vaccines will be used, as well as access to the appropriate diagnostic tools to underpin these campaigns.