Evaluation of direct immunofluorescence test for campylobacter fetus in Bulls experimentally infected and comensal bacteria from the reproductive tract of bulls

Campylobacter fetus is a Gram negative bacterium, with 2 relevant subspecies for cattle health: C. fetus subsp. fetus (Cff) and C. fetus subsp. venerealis (Cfv) which cause important reproductive losses. In the present work, four groups of bulls were used: one group to characterize the genital micro...

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Detalles Bibliográficos
Autores: García, Juan Agustín, Soto, J., Soto, P., Malena, Rosana, Morsella, Claudia, Méndez, Maria Alejandra, Fiorentino, Maria Andrea, Paz Acuña, Joaquín Roberto, Lucchesi, Enrique, Paolicchi, Fernando Alberto
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/175999
Acceso en línea:http://hdl.handle.net/11336/175999
Access Level:acceso abierto
Palabra clave:BOVINE GENITAL CAMPYLOBACTERIOSIS
RUMINANTS
VENEREAL DISEASE
ABORTIONS
INFERTILITY
https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
Descripción
Sumario:Campylobacter fetus is a Gram negative bacterium, with 2 relevant subspecies for cattle health: C. fetus subsp. fetus (Cff) and C. fetus subsp. venerealis (Cfv) which cause important reproductive losses. In the present work, four groups of bulls were used: one group to characterize the genital microbiota (G1; n=3) and the other three to evaluate the direct immunofluorescence (DIF) test for the diagnosis of bovine campylobacteriosis in preputial samples (PS) from experimentally infected bulls with Cff (G2; n=3) and Cfv (G3; n=3), and controls (G4; n=4). Seven bacterial strains of different genera were identified in the PS from G1. Other 11 laboratory bacterial strains were included: Cff, Cfv and Cfv biovar Intermedius, 3 Campylobacter non-fetus, 3 Gram negative and 2 Gram positive. Only the C. fetus strains presented positive immunostaining. The sensitivity and specificity of the DIF test were 79 % and 100 %, respectively. Concordance between DIF test and bacteriological culture was 83 % (Kappa index: 0.65). The present study shows the high specificity of the DIF test for detection of C. fetus using a fluorescent conjugate elaborated in Argentina, and highlights the relevance of no cross reaction against 15 bacterial strains normally present in bull preputial microbiota.