A Conformational Model for MTPA Esters of Chiral N-(2-Hydroxyalkyl)acrylamides
The absolute stereochemistry of novel chiral N-(2-hycroxyalkyl)acrylamides prepared by a lipase-catalyzed resolution was successfully determined by 1H NMR of their MTPA esters. The method was validated for this particular case by computational experiments.
| Autores: | , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2014 |
| País: | Argentina |
| Recursos: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositório: | CONICET Digital (CONICET) |
| Idioma: | inglês |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/18704 |
| Acesso em linha: | http://hdl.handle.net/11336/18704 |
| Access Level: | Acceso aberto |
| Palavra-chave: | ABSOLUTE STEREOCHEMISTRY CHIRAL ACRYLAMIDES LIPASE-CATALYZED https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| Resumo: | The absolute stereochemistry of novel chiral N-(2-hycroxyalkyl)acrylamides prepared by a lipase-catalyzed resolution was successfully determined by 1H NMR of their MTPA esters. The method was validated for this particular case by computational experiments. |
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