Electrophysiologic study of globus pallidus projections to the thalamic reticular nucleus
This study was designed to explore the electrophysiological relationships between the globus pallidus (GP), the substantia nigra pars reticulata (SNr) and the thalamic reticular nucleus (TRN) in urethaneanesthetized rats. The neuronal activity of the rostral part of the TRN was recorded by microelec...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2013 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/1920 |
| Acceso en línea: | http://hdl.handle.net/11336/1920 |
| Access Level: | acceso abierto |
| Palabra clave: | Electrical And Chemical Stimulation Reticular Thalamic Nucleus Globus Pallidus Palidoreticular Pathway https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
| Sumario: | This study was designed to explore the electrophysiological relationships between the globus pallidus (GP), the substantia nigra pars reticulata (SNr) and the thalamic reticular nucleus (TRN) in urethaneanesthetized rats. The neuronal activity of the rostral part of the TRN was recorded by microelectrodes.Single pulse electrical stimulation of the GP and SNr produced inhibition of the spontaneous activity of the majority of TRN neurons. Stimulation of the GP by microinjections of bicuculline (25 ng/300 nl) produced also inhibition of the spontaneous activity of the reticular neurons. This could lead to facilitation of the cerebral cortex, as the reticular nucleus is reciprocally connected to, and inhibits, the thalamic motor nuclei, that in turn excite the motor cortex. |
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