Carotid Intima Media Thickness Reference Intervals for a Healthy Argentinean Population Aged 11-81 Years

Reference intervals (RIs) of carotid intima media thickness (CIMT) from large healthy population are still lacking in Latin America. The aim of this study was to determine CIMT RIs in a cohort of 1012 healthy subjects from Argentina. We evaluated if RIs for males and females and for left and right c...

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Bibliographic Details
Authors: Diaz, Alberto Alejandro, Bia, Daniel, Zócalo, Yanina, Manterola, Hugo Luis, Larrabide, Ignacio, Lo Vercio, Lucas, del Fresno, Mirta Mariana, Cabrera Fischer, Edmundo Ignacio
Format: article
Status:Published version
Publication Date:2018
Country:Argentina
Institution:Consejo Nacional de Investigaciones Científicas y Técnicas
Repository:CONICET Digital (CONICET)
Language:English
OAI Identifier:oai:ri.conicet.gov.ar:11336/95913
Online Access:http://hdl.handle.net/11336/95913
Access Level:Open access
Keyword:INTIMA MEDIA THICKNESS
REFERENCE INTERVALS
IMT
ADOLESCENTS
https://purl.org/becyt/ford/3.5
https://purl.org/becyt/ford/3
Description
Summary:Reference intervals (RIs) of carotid intima media thickness (CIMT) from large healthy population are still lacking in Latin America. The aim of this study was to determine CIMT RIs in a cohort of 1012 healthy subjects from Argentina. We evaluated if RIs for males and females and for left and right carotids were necessary. Second, mean and standard deviation (SD) age-related equations were obtained for left, right, and average (left + right)/2) CIMT using parametric regression methods based on fractional polynomials, in order to obtain age-specific percentiles curves. Age-specific percentile curves were obtained. Males showed higher A-CIMT ( mm versus  mm, ) in comparison with females. For males, the equations were as follows: A-CIMT mean = 0.42 + ; A-CIMT SD = 5.9 × 10−2 + . For females, they were as follows: A-CIMT mean = 0.40 + ; A-CIMT SD = 4.67 × 10−2 + . Our study provides the largest database concerning RIs of CIMT in healthy people in Argentina. Specific RIs and percentiles of CIMT for children, adolescents, and adults are now available according to age and gender, for right and left common carotid arteries.

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