Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map

The turbot (Scophthalmus maximus) is a species of great relevance to European aquaculture and hence might benefit from enhanced genomic resources. The aim of this study was to integrate all previous turbot mapping resources to obtain a dense consensus genetic map. A total of 514 single nucleotide po...

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Detalhes bibliográficos
Autores: Hermida, Miguel, Bouza, Carmen, Fernández, Carlos, Sciara, Andres Angel, Rodríguez Ramilo, Silvia T., Fernández, Jesús, Martinez, Paulino
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/4858
Acesso em linha:http://hdl.handle.net/11336/4858
Access Level:acceso abierto
Palavra-chave:Turbot
Genetic Map
Consensus
Qtl
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
id AR_7d868e364ffcf76887ad5b69fbc4e859
oai_identifier_str oai:ri.conicet.gov.ar:11336/4858
network_acronym_str AR
network_name_str Argentina
repository_id_str
dc.title.none.fl_str_mv Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map
title Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map
spellingShingle Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map
Hermida, Miguel
Turbot
Genetic Map
Consensus
Qtl
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
title_short Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map
title_full Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map
title_fullStr Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map
title_full_unstemmed Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map
title_sort Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map
dc.creator.none.fl_str_mv Hermida, Miguel
Bouza, Carmen
Fernández, Carlos
Sciara, Andres Angel
Rodríguez Ramilo, Silvia T.
Fernández, Jesús
Martinez, Paulino
author Hermida, Miguel
author_facet Hermida, Miguel
Bouza, Carmen
Fernández, Carlos
Sciara, Andres Angel
Rodríguez Ramilo, Silvia T.
Fernández, Jesús
Martinez, Paulino
author_role author
author2 Bouza, Carmen
Fernández, Carlos
Sciara, Andres Angel
Rodríguez Ramilo, Silvia T.
Fernández, Jesús
Martinez, Paulino
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Turbot
Genetic Map
Consensus
Qtl
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
topic Turbot
Genetic Map
Consensus
Qtl
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
description The turbot (Scophthalmus maximus) is a species of great relevance to European aquaculture and hence might benefit from enhanced genomic resources. The aim of this study was to integrate all previous turbot mapping resources to obtain a dense consensus genetic map. A total of 514 single nucleotide polymorphisms (SNP) and microsatellite markers from reported turbot genetic maps, were used for map construction. Among these markers, 487 (LOD score > 3), including 39% expressed sequence tag (EST)-linked and 61% anonymous, were integrated in 24 linkage groups. The linkage map comprised a total length of 1414 cM (1274.4 cM framework) with 3.3 cM (3.6 cM framework) inter-marker distance, representing an estimated genomic coverage of ~ 90%. This map was used to refine quantitative trait loci (QTL) screening for sex, because of the relevance of this trait for the turbot industry, which confirmed not only the main sex-determining region at linkage group (LG) 5, but also the involvement of additional significant genetic factors at other linkage groups. Comparative mapping supported the macrosyntenic pattern previously observed when comparing turbot and model fish genomes and enabled identification of candidate genes related to sexual development and reproduction at LG5, such as DNAJC19 and Sox2. The available number of markers in the turbot map could be easily increased to 592 because of the established correspondence between linkage groups of the two main genetic maps, thus approaching 1 marker/Mb based on the turbot genome size. This map represents a useful tool for evolutionary studies and for supporting ongoing marker-assisted selection programs in this species.
publishDate 2013
dc.date.none.fl_str_mv 2013-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/4858
Hermida, Miguel; Bouza, Carmen; Fernández, Carlos; Sciara, Andres Angel; Rodríguez Ramilo, Silvia T.; et al.; Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map; Elsevier; Aquaculture; 414-415; 11-2013; 19-25
0044-8486
url http://hdl.handle.net/11336/4858
identifier_str_mv Hermida, Miguel; Bouza, Carmen; Fernández, Carlos; Sciara, Andres Angel; Rodríguez Ramilo, Silvia T.; et al.; Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map; Elsevier; Aquaculture; 414-415; 11-2013; 19-25
0044-8486
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0044848613003785
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.aquaculture.2013.07.040
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1799195424345554944
spelling Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic mapHermida, MiguelBouza, CarmenFernández, CarlosSciara, Andres AngelRodríguez Ramilo, Silvia T.Fernández, JesúsMartinez, PaulinoTurbotGenetic MapConsensusQtlhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1https://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The turbot (Scophthalmus maximus) is a species of great relevance to European aquaculture and hence might benefit from enhanced genomic resources. The aim of this study was to integrate all previous turbot mapping resources to obtain a dense consensus genetic map. A total of 514 single nucleotide polymorphisms (SNP) and microsatellite markers from reported turbot genetic maps, were used for map construction. Among these markers, 487 (LOD score > 3), including 39% expressed sequence tag (EST)-linked and 61% anonymous, were integrated in 24 linkage groups. The linkage map comprised a total length of 1414 cM (1274.4 cM framework) with 3.3 cM (3.6 cM framework) inter-marker distance, representing an estimated genomic coverage of ~ 90%. This map was used to refine quantitative trait loci (QTL) screening for sex, because of the relevance of this trait for the turbot industry, which confirmed not only the main sex-determining region at linkage group (LG) 5, but also the involvement of additional significant genetic factors at other linkage groups. Comparative mapping supported the macrosyntenic pattern previously observed when comparing turbot and model fish genomes and enabled identification of candidate genes related to sexual development and reproduction at LG5, such as DNAJC19 and Sox2. The available number of markers in the turbot map could be easily increased to 592 because of the established correspondence between linkage groups of the two main genetic maps, thus approaching 1 marker/Mb based on the turbot genome size. This map represents a useful tool for evolutionary studies and for supporting ongoing marker-assisted selection programs in this species.Fil: Hermida, Miguel. Universidad de Santiago de Compostela. Facultad de Veterinaria. Departamento de Genética; EspañaFil: Bouza, Carmen. Universidad de Santiago de Compostela. Facultad de Veterinaria. Departamento de Genética; EspañaFil: Fernández, Carlos. Universidad de Santiago de Compostela. Facultad de Veterinaria. Departamento de Genética; EspañaFil: Sciara, Andres Angel. Universidad de Santiago de Compostela. Facultad de Veterinaria. Departamento de Genética; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Rodríguez Ramilo, Silvia T.. Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Departamento de Mejora Genética Animal; EspañaFil: Fernández, Jesús. Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Departamento de Mejora Genética Animal; EspañaFil: Martinez, Paulino. Universidad de Santiago de Compostela. Facultad de Veterinaria. Departamento de Genética; EspañaElsevier2013-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/4858Hermida, Miguel; Bouza, Carmen; Fernández, Carlos; Sciara, Andres Angel; Rodríguez Ramilo, Silvia T.; et al.; Compilation of mapping resources in turbot (Scophthalmus maximus): A new integrated consensus genetic map; Elsevier; Aquaculture; 414-415; 11-2013; 19-250044-8486enginfo:eu-repo/semantics/altIdentifier/doi/info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0044848613003785info:eu-repo/semantics/altIdentifier/doi/10.1016/j.aquaculture.2013.07.040info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:52:06Zoai:ri.conicet.gov.ar:11336/4858instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:52:06.418CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
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