Immune Response Modulation by Tumor-Secreted Glycosphingolipids

Although originally considered merely structural components of cellular membranes, glycosphingolipids (GSL) arenow recognized as having critical effects on cellular physiology, including proliferation, differentiation, viraltransformation and ontogenesis. In addition, a vast majority of human cancer...

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Detalles Bibliográficos
Autores: Lardone, Ricardo Dante, Cely, Ingrid, Sieling, Peter A., Lee, Delphine
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/32113
Acceso en línea:http://hdl.handle.net/11336/32113
Access Level:acceso abierto
Palabra clave:Glycosphingolipids
Anti-tumor immunity
Cancer
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
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spelling Immune Response Modulation by Tumor-Secreted GlycosphingolipidsLardone, Ricardo DanteCely, IngridSieling, Peter A.Lee, DelphineGlycosphingolipidsAnti-tumor immunityCancerhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Although originally considered merely structural components of cellular membranes, glycosphingolipids (GSL) arenow recognized as having critical effects on cellular physiology, including proliferation, differentiation, viraltransformation and ontogenesis. In addition, a vast majority of human cancers have modified GSL compositioncompared to parental normal cells. These modifications may contribute to both tumor survival and exert strikingeffects on anti-tumor immunity. In this review, we discuss mechanisms of immune modulation by tumor-secreted GSL.Fil: Lardone, Ricardo Dante. John Wayne Cancer Institute at Providence Saint John’s Health Center. Santa Monica; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Química Biológica de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Centro de Investigaciones en Química Biológica de Córdoba; ArgentinaFil: Cely, Ingrid. John Wayne Cancer Institute at Providence Saint John’s Health Center. Santa Monica; Estados UnidosFil: Sieling, Peter A.. John Wayne Cancer Institute at Providence Saint John’s Health Center. Santa Monica; Estados UnidosFil: Lee, Delphine. John Wayne Cancer Institute at Providence Saint John’s Health Center. Santa Monica; Estados UnidosOmics Group International2014-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/32113Lee, Delphine; Sieling, Peter A.; Cely, Ingrid; Lardone, Ricardo Dante; Immune Response Modulation by Tumor-Secreted Glycosphingolipids; Omics Group International; Journal of Glycobiology; 3; 107; 4-20142168-958XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.omicsonline.org/open-access/immune-response-modulation-by-tumorsecreted-glycosphingolipids-2168-958X-3-107.php?aid=30322info:eu-repo/semantics/altIdentifier/doi/10.4172/2168-958X.1000107info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:33:21Zoai:ri.conicet.gov.ar:11336/32113instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:33:21.942CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Immune Response Modulation by Tumor-Secreted Glycosphingolipids
title Immune Response Modulation by Tumor-Secreted Glycosphingolipids
spellingShingle Immune Response Modulation by Tumor-Secreted Glycosphingolipids
Lardone, Ricardo Dante
Glycosphingolipids
Anti-tumor immunity
Cancer
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
title_short Immune Response Modulation by Tumor-Secreted Glycosphingolipids
title_full Immune Response Modulation by Tumor-Secreted Glycosphingolipids
title_fullStr Immune Response Modulation by Tumor-Secreted Glycosphingolipids
title_full_unstemmed Immune Response Modulation by Tumor-Secreted Glycosphingolipids
title_sort Immune Response Modulation by Tumor-Secreted Glycosphingolipids
dc.creator.none.fl_str_mv Lardone, Ricardo Dante
Cely, Ingrid
Sieling, Peter A.
Lee, Delphine
author Lardone, Ricardo Dante
author_facet Lardone, Ricardo Dante
Cely, Ingrid
Sieling, Peter A.
Lee, Delphine
author_role author
author2 Cely, Ingrid
Sieling, Peter A.
Lee, Delphine
author2_role author
author
author
dc.subject.none.fl_str_mv Glycosphingolipids
Anti-tumor immunity
Cancer
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
topic Glycosphingolipids
Anti-tumor immunity
Cancer
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
description Although originally considered merely structural components of cellular membranes, glycosphingolipids (GSL) arenow recognized as having critical effects on cellular physiology, including proliferation, differentiation, viraltransformation and ontogenesis. In addition, a vast majority of human cancers have modified GSL compositioncompared to parental normal cells. These modifications may contribute to both tumor survival and exert strikingeffects on anti-tumor immunity. In this review, we discuss mechanisms of immune modulation by tumor-secreted GSL.
publishDate 2014
dc.date.none.fl_str_mv 2014-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/32113
Lee, Delphine; Sieling, Peter A.; Cely, Ingrid; Lardone, Ricardo Dante; Immune Response Modulation by Tumor-Secreted Glycosphingolipids; Omics Group International; Journal of Glycobiology; 3; 107; 4-2014
2168-958X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/32113
identifier_str_mv Lee, Delphine; Sieling, Peter A.; Cely, Ingrid; Lardone, Ricardo Dante; Immune Response Modulation by Tumor-Secreted Glycosphingolipids; Omics Group International; Journal of Glycobiology; 3; 107; 4-2014
2168-958X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.omicsonline.org/open-access/immune-response-modulation-by-tumorsecreted-glycosphingolipids-2168-958X-3-107.php?aid=30322
info:eu-repo/semantics/altIdentifier/doi/10.4172/2168-958X.1000107
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Omics Group International
publisher.none.fl_str_mv Omics Group International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 15.812429

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