Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)

Animals living in nontropical climates modify their physiology and behavior to adapt to seasonal environmental changes. Part of this adaptation involves the release of catecholamine from sympathetic nerve endings and the adrenal medulla, which play a major role in regulating energy balance. The aim...

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Detalles Bibliográficos
Autores: Rodriguez, Hugo, Filippa, Veronica Palmira, Penissi, Alicia Beatriz, Fogal, Teresa Hilda, Dominguez, Susana, Piezzi, Ramon Salvador, Scardapane, Luis A.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/7564
Acceso en línea:http://hdl.handle.net/11336/7564
Access Level:acceso abierto
Palabra clave:Adrenal
Medulla
Epinephrine
Chromaffin
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
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oai_identifier_str oai:ri.conicet.gov.ar:11336/7564
network_acronym_str AR
network_name_str Argentina
repository_id_str
dc.title.none.fl_str_mv Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)
title Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)
spellingShingle Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)
Rodriguez, Hugo
Adrenal
Medulla
Epinephrine
Chromaffin
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
title_short Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)
title_full Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)
title_fullStr Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)
title_full_unstemmed Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)
title_sort Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)
dc.creator.none.fl_str_mv Rodriguez, Hugo
Filippa, Veronica Palmira
Penissi, Alicia Beatriz
Fogal, Teresa Hilda
Dominguez, Susana
Piezzi, Ramon Salvador
Scardapane, Luis A.
author Rodriguez, Hugo
author_facet Rodriguez, Hugo
Filippa, Veronica Palmira
Penissi, Alicia Beatriz
Fogal, Teresa Hilda
Dominguez, Susana
Piezzi, Ramon Salvador
Scardapane, Luis A.
author_role author
author2 Filippa, Veronica Palmira
Penissi, Alicia Beatriz
Fogal, Teresa Hilda
Dominguez, Susana
Piezzi, Ramon Salvador
Scardapane, Luis A.
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Adrenal
Medulla
Epinephrine
Chromaffin
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
topic Adrenal
Medulla
Epinephrine
Chromaffin
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
description Animals living in nontropical climates modify their physiology and behavior to adapt to seasonal environmental changes. Part of this adaptation involves the release of catecholamine from sympathetic nerve endings and the adrenal medulla, which play a major role in regulating energy balance. The aim of this work was to investigate whether adult male viscachas in their natural habitat exhibits structural changes in the adrenal medulla during the annual seasonal cycle. In August-September, chromaffin granules revealed ultrastructural changes suggestive of piecemeal degranulation. Quantitative morphometric analysis by transmission electron microscopy showed a significantly lower percentage of resting chromaffin granules and a higher percentage of altered granules and empty containers in August-September (late winter) compared to February-March (late summer), suggesting an increased secretory process of catecholamines in August-September. The mechanism of piecemeal degranulation might amplify this process, encouraging the adaptive response to winter environmental conditions. Tissue levels of epinephrine, norepinephrine, and dopamine (analyzed by high-performance liquid chromatography) changed throughout the year, reaching maximum values in February-March and minimum values in August-September. These results demonstrate morphological and biochemical seasonal variations of the adrenal medulla, suggesting that epinephrine might promote energy mobilization, which allow the Lagostomus to cope with adverse environmental conditions and thus to survive during winter season.
publishDate 2013
dc.date.none.fl_str_mv 2013-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/7564
Rodriguez, Hugo; Filippa, Veronica Palmira; Penissi, Alicia Beatriz; Fogal, Teresa Hilda; Dominguez, Susana; et al.; Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus); Wiley; Anatomical Record-advances In Integrative Anatomy And Evolutionary Biology; 296; 7; 4-2013; 1089-1095
1932-8486
url http://hdl.handle.net/11336/7564
identifier_str_mv Rodriguez, Hugo; Filippa, Veronica Palmira; Penissi, Alicia Beatriz; Fogal, Teresa Hilda; Dominguez, Susana; et al.; Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus); Wiley; Anatomical Record-advances In Integrative Anatomy And Evolutionary Biology; 296; 7; 4-2013; 1089-1095
1932-8486
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/ar.22707/abstract
info:eu-repo/semantics/altIdentifier/doi/10.1002/ar.22707
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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spelling Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)Rodriguez, HugoFilippa, Veronica PalmiraPenissi, Alicia BeatrizFogal, Teresa HildaDominguez, SusanaPiezzi, Ramon SalvadorScardapane, Luis A.AdrenalMedullaEpinephrineChromaffinhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Animals living in nontropical climates modify their physiology and behavior to adapt to seasonal environmental changes. Part of this adaptation involves the release of catecholamine from sympathetic nerve endings and the adrenal medulla, which play a major role in regulating energy balance. The aim of this work was to investigate whether adult male viscachas in their natural habitat exhibits structural changes in the adrenal medulla during the annual seasonal cycle. In August-September, chromaffin granules revealed ultrastructural changes suggestive of piecemeal degranulation. Quantitative morphometric analysis by transmission electron microscopy showed a significantly lower percentage of resting chromaffin granules and a higher percentage of altered granules and empty containers in August-September (late winter) compared to February-March (late summer), suggesting an increased secretory process of catecholamines in August-September. The mechanism of piecemeal degranulation might amplify this process, encouraging the adaptive response to winter environmental conditions. Tissue levels of epinephrine, norepinephrine, and dopamine (analyzed by high-performance liquid chromatography) changed throughout the year, reaching maximum values in February-March and minimum values in August-September. These results demonstrate morphological and biochemical seasonal variations of the adrenal medulla, suggesting that epinephrine might promote energy mobilization, which allow the Lagostomus to cope with adverse environmental conditions and thus to survive during winter season.Fil: Rodriguez, Hugo. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; ArgentinaFil: Filippa, Veronica Palmira. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; ArgentinaFil: Penissi, Alicia Beatriz. Universidad Nacional de Cuyo. Facultad de Cs.medicas. Instituto de Histologia y Embriologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Fogal, Teresa Hilda. Universidad Nacional de Cuyo; ArgentinaFil: Dominguez, Susana. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Area Ecológica; ArgentinaFil: Piezzi, Ramon Salvador. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo; ArgentinaFil: Scardapane, Luis A.. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; ArgentinaWiley2013-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/7564Rodriguez, Hugo; Filippa, Veronica Palmira; Penissi, Alicia Beatriz; Fogal, Teresa Hilda; Dominguez, Susana; et al.; Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus); Wiley; Anatomical Record-advances In Integrative Anatomy And Evolutionary Biology; 296; 7; 4-2013; 1089-10951932-8486enginfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/ar.22707/abstractinfo:eu-repo/semantics/altIdentifier/doi/10.1002/ar.22707info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:43:24Zoai:ri.conicet.gov.ar:11336/7564instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:43:24.33CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
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