Hemolytic uremic syndrome: co-infection with two different serotypes of shiga-like toxin producing escherichia coli

We report a case of a child who developed Hemolytic Uremic Syndrome in whom two Shiga-like toxin (SLT)-producing Escherichia coli strains of different serotypes and genotypes, were simultaneously isolated from stools. In addition, one of these strains represented a new toxin producing serotype. Stra...

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Detalles Bibliográficos
Autores: Rivas, Marta, Voyer, L., Tous, Mónica, Leardini, Nelida, de Mena, María F., Wainsztein, Raquel, Callejo, Raquel, Prado, Valeria, Binsztein, Norma
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1993
País:Argentina
Institución:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
Repositorio:Sistema de Gestión del Conocimiento ANLIS MALBRÁN
Idioma:inglés
OAI Identifier:oai:sgc.anlis.gob.ar:123456789/96
Acceso en línea:http://sgc.anlis.gob.ar/handle/123456789/96
http://books.google.com.ar/books?hl=es&lr=&id=JdLvG9AGhBYC&oi=fnd&pg=PA487&dq=Hemolytic+uremic+syndrome:+co-infection+with+two+different+serotypes+of+Shiga-like+toxin+producing+Escherichia+coli&ots=Tc95V146gY&sig=qSmOfM9Z-I8wh2aNKc8KzdYIuX0#v=onepage&q=Hemolytic%20uremic%20syndrome%3A%20co-infection%20with%20two%20different%20serotypes%20of%20Shiga-like%20toxin%20producing%20Escherichia%20coli&f=false
Access Level:acceso abierto
Palabra clave:Síndrome Hemolítico-Urémico
Escherichia coli
Descripción
Sumario:We report a case of a child who developed Hemolytic Uremic Syndrome in whom two Shiga-like toxin (SLT)-producing Escherichia coli strains of different serotypes and genotypes, were simultaneously isolated from stools. In addition, one of these strains represented a new toxin producing serotype. Strain 1 belonged to serotype O157: H7, biotype D, produced SLT II and was susceptible to all antibiotics tested. This strain hybridized with gene probes for SLT II, fimbrial adhesion (EHEC factor) and attaching and effacing factor (eae). Strain 2 belonged to serotype 025: K2: H2, produced SLT II and had a multiresistant antibiotic susceptibility pattern. This strain hybridized with the EHEC gene probe but not with SLT I, SLT II and eae gene probes. Free fecal SLT II cytotoxin was detected in stools of the child and his father, suggesting that the infection may have been acquired from a household contact.