Stimuli-responsive materials for tissue engineering and drug delivery

Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions,...

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Detalhes bibliográficos
Autores: Municoy, Sofia, Alvarez Echazú, María Inés, Antezana, Pablo Edmundo, Galdopórpora, Juan Manuel, Olivetti, Christian Ezequiel, Mebert, Andrea Mathilde, Foglia, María Lucía, Tuttolomondo, María Victoria, Alvarez, Gisela Solange, Hardy, John, Desimone, Martín Federico
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/135274
Acesso em linha:http://hdl.handle.net/11336/135274
Access Level:acceso abierto
Palavra-chave:BIOMATERIALS
DRUG DELIVERY
LIGHT-RESPONSIVE
PH-RESPONSIVE
REDOX-RESPONSIVE
STIMULI-RESPONSIVE MATERIALS
THERMORESPONSIVE
TISSUE ENGINEERING
https://purl.org/becyt/ford/3.4
https://purl.org/becyt/ford/3
Descrição
Resumo:Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions, structure, and/or dimensions. The specificity of stimuli response, and ability to respond to endogenous cues inherently present in living systems provide possibilities to develop novel tissue engineering and drug delivery strategies (for example materials composed of stimuli responsive polymers that self-assemble or undergo phase transitions or morphology transformations). Herein, smart materials as controlled drug release vehicles for tissue engineering are described, highlighting their potential for the delivery of precise quantities of drugs at specific locations and times promoting the controlled repair or remodeling of tissues.