Permutation Entropy Applied to the Characterization of the Clinical Evolution of Epileptic Patients under Pharmacological Treatment

Different techniques originated in information theory and tools from nonlinear systems theory have been applied to the analysis of electro-physiological time series. Several clinically relevant results have emerged from the use of concepts, such as entropy, chaos and complexity, in analyzing electro...

ver descrição completa

Detalhes bibliográficos
Autores: Mateos, Diego Martín, Juan Manuel Díaz, Lamberti, Pedro Walter
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/35040
Acesso em linha:http://hdl.handle.net/11336/35040
Access Level:acceso abierto
Palavra-chave:Entropía de Permutación
Electroencefalogramas
Evolución clinica
https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
Descrição
Resumo:Different techniques originated in information theory and tools from nonlinear systems theory have been applied to the analysis of electro-physiological time series. Several clinically relevant results have emerged from the use of concepts, such as entropy, chaos and complexity, in analyzing electrocardiograms and electroencephalographic (EEG) records. In this work, we develop a method based on permutation entropy (PE) to characterize EEG records from different stages in the treatment of a chronic epileptic patient. Our results show that the PE is useful for clearly quantifying the evolution of the patient along a certain lapse of time and allows visualizing in a very convenient way the effects of the pharmacotherapy.