Population genetic analyses of the Powerplex Fusion kit in a cosmopolitan sample of Chubut province (Patagonia Argentina)

Allele frequencies and forensic parameters for 22 autosomal STR loci and DYS391 locus included in the PowerPlex® Fusion System kit were estimated in a sample of 770 unrelated individuals from Chubut province, southern Patagonia. No significant deviations from Hardy-Weinberg equilibrium were observed...

Descripción completa

Detalles Bibliográficos
Autores: Parolin, María Laura, Real, Luciano Esteban, Martinazzo Giménez, Liza Beatriz, Basso, Nestor Guillermo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/40715
Acceso en línea:http://hdl.handle.net/11336/40715
Access Level:acceso abierto
Palabra clave:Chubut
Poweplex Fusion
Str
Forensic
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
Descripción
Sumario:Allele frequencies and forensic parameters for 22 autosomal STR loci and DYS391 locus included in the PowerPlex® Fusion System kit were estimated in a sample of 770 unrelated individuals from Chubut province, southern Patagonia. No significant deviations from Hardy-Weinberg equilibrium were observed after Bonferroni?s correction. The combined power of discrimination and the combined probability of exclusion were >0.999999 and 0.999984, respectively. Comparisons with other worldwide populations were performed. The MDS obtained show a close biological relation between Chubut and Chile. The estimated interethnic admixture supports a high Native American contribution (46%) in the population sample of Chubut. These results enlarge the Argentine databases of autosomal STR and would provide a valuable contribution for identification tests and population genetic studies.