A catalyst-free synthesis of asymmetric diaryl ketones from aryltins

A series of diaryl ketones have been synthesized in good yields (40–78%) through the catalyst-free reaction of trimethylarylstannanes with aroyl chlorides in chlorobenzene as solvent. In addition, an attractive feature is that these reactions are completely regioselective making possible the synthes...

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Detalhes bibliográficos
Autores: Silbestri, Gustavo Fabián, Bogel Masson, Romina, Lockhart, María Teresa, Chopa, Alicia Beatriz
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/81917
Acesso em linha:http://hdl.handle.net/11336/81917
Access Level:acceso abierto
Palavra-chave:https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descrição
Resumo:A series of diaryl ketones have been synthesized in good yields (40–78%) through the catalyst-free reaction of trimethylarylstannanes with aroyl chlorides in chlorobenzene as solvent. In addition, an attractive feature is that these reactions are completely regioselective making possible the synthesis of diarylketones which are not usually available under the influence of the directing forces of the substituents present in the aromatic ring. Also, the reaction conditions are mild enough to be applied to acid sensitive molecules.