Evaluation of fungal-specific fluorescent labeled echinocandin probes as diagnostic adjuncts

The diagnosis of invasive fungal infections from radiographic imaging is non-specific and problematic. As a first step toward increasing specificity, we describe the development of a broad-spectrum fungal-specific targeting molecule, which when modified with a fluorescent label fully retains its tar...

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Detalles Bibliográficos
Autores: Pratt, Ayiasha, Garcia, Guillermo Manuel, Zhao, Yanan, Park, Steven, Mustaev, Arkady, Pillai, Shyamala, Perlin, David S.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/6377
Acceso en línea:http://hdl.handle.net/11336/6377
Access Level:acceso abierto
Palabra clave:Candida
Diagnostics
Echinocandins
Fluorescence Labeled Antifungal
https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
Descripción
Sumario:The diagnosis of invasive fungal infections from radiographic imaging is non-specific and problematic. As a first step toward increasing specificity, we describe the development of a broad-spectrum fungal-specific targeting molecule, which when modified with a fluorescent label fully retains its targeting properties, and provides a basis for future imaging applications.