Current advances in electrospun gelatin-based scaffolds for tissue engineering applications

The development of biomimetic highly-porous scaffolds is essential for successful tissue engineering. Electrospun nanofibers are highly versatile platforms for a broad range of applications in different research areas. In the biomedical field, micro/nanoscale fibrous structures have gained great int...

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Detalles Bibliográficos
Autores: Aldana, Ana Agustina, Abraham, Gustavo Abel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/30622
Acceso en línea:http://hdl.handle.net/11336/30622
Access Level:acceso embargado
Palabra clave:Gelatin
Electrospun scaffolds
Tissue engineering
Biopolymers
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
Descripción
Sumario:The development of biomimetic highly-porous scaffolds is essential for successful tissue engineering. Electrospun nanofibers are highly versatile platforms for a broad range of applications in different research areas. In the biomedical field, micro/nanoscale fibrous structures have gained great interest for wound dressings, drug delivery systems, soft and hard-tissue engineering scaffolds, enzyme immobilization, among other healthcare applications. In this mini-review, electrospun gelatin-based scaffolds for a variety of tissue engineering applications, such as bone, cartilage, skin, nerve, and ocular and vascular tissue engineering, are reviewed and discussed. Gelatin blends with natural or synthetic polymers exhibit physicochemical, biomechanical, and biocompatibility properties very attractive for scaffolding. Current advances and challenges on this research field are presented.