Regulation of skeletal muscle phosphorylase phosphatase activity. II. Interconversions
1. 1. The incubation of the pegion breast muscle homogenate at 37° resulted in a time-dependent decrease in phosphatase activity. This effect was stimulated by ATP, ADP, AMP, GTP, UTP, CTP or pyrophosphate. 2. 2. Reactivation of an inactive phosphorylase a phosphatase preparation was obtained by inc...
| Autores: | , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 1970 |
| País: | Argentina |
| Institución: | Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales |
| Repositorio: | Biblioteca Digital (UBA-FCEN) |
| Idioma: | inglés |
| OAI Identifier: | paperaa:paper_00052744_v198_n3_p504_Chelala |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00052744_v198_n3_p504_Chelala |
| Access Level: | acceso abierto |
| Palabra clave: | adenine nucleotide adenosine triphosphate creatine phosphate cyclic AMP glucosyltransferase guanine nucleotide magnesium mercaptoethanol phosphatase phosphorus pyrimidine nucleotide pyrophosphate animal article enzyme activation enzymology muscle pigeon Adenine Nucleotides Adenosine Triphosphate Animal Cyclic AMP Cytosine Nucleotides Diphosphates Enzyme Activation Glucosyltransferases Guanine Nucleotides Magnesium Mercaptoethanol Muscles Phosphocreatine Phosphoric Monoester Hydrolases Phosphorus Isotopes Pigeons Uracil Nucleotides |
| Sumario: | 1. 1. The incubation of the pegion breast muscle homogenate at 37° resulted in a time-dependent decrease in phosphatase activity. This effect was stimulated by ATP, ADP, AMP, GTP, UTP, CTP or pyrophosphate. 2. 2. Reactivation of an inactive phosphorylase a phosphatase preparation was obtained by incubation with ATP-Mg2+. Phosphocreatine-Mg2+ or Mg2+ were also found to be effective in bringing about the reactivation of the enzyme. 3. 3. 3′,5′-Cyclic AMP decreased the yield of the active enzyme when it was added either at the beginning or during the activation reaction. © 1970. |
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