Inhibition of goiter growth and of cyclic AMP formation in rat thyroid by 2-iodohexadecanal

Thyroid autoregulation has been related to intraglandular content of an unknown putative iodocompound. The thyroid is capable of producing different iodolipids such as 6-iodo-deltalactone (ILdelta) and 2-iodohexadecanal (2-IHDA). Data from different laboratories have shown that these iodolipids inhi...

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Detalles Bibliográficos
Autores: Thomasz, Lisa, Oglio, Romina, Toro Rivandeira, D., Dagrosa, María Alejandra, Jahn, Graciela Alma, Pignataro, Omar Pedro, Sartorio, G., Pisarev, Mario Alberto, Juvenal, Guillermo Juan
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/25077
Acceso en línea:http://hdl.handle.net/11336/25077
Access Level:acceso abierto
Palabra clave:Antigoitrogenics
Iodolipids
Thyroid
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
Descripción
Sumario:Thyroid autoregulation has been related to intraglandular content of an unknown putative iodocompound. The thyroid is capable of producing different iodolipids such as 6-iodo-deltalactone (ILdelta) and 2-iodohexadecanal (2-IHDA). Data from different laboratories have shown that these iodolipids inhibit several thyroid parameters. ILdelta has an antigoitrogenic action but no data about the action of 2-IHDA on this parameter has been published.

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