Photoreceptor Contributions to the Human Pupil Light Reflex

The pupil reacts to the amount of light reaching the eye. It reduces its size when the light is high and dilates at low light levels to allow the entrance of more photons. This behavior is called pupil light reflex (PLR). Recent investigations in humans were conducted to understand how the photorece...

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Detalles Bibliográficos
Autores: Barrionuevo, Pablo Alejandro, Issolio, Luis Alberto, Tripolone, María Constanza
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/232963
Acceso en línea:http://hdl.handle.net/11336/232963
Access Level:acceso abierto
Palabra clave:PUPIL
PHOTORECEPTORS
HUMANS
RETINA
PUPILLOMETRY
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/3.1
Descripción
Sumario:The pupil reacts to the amount of light reaching the eye. It reduces its size when the light is high and dilates at low light levels to allow the entrance of more photons. This behavior is called pupil light reflex (PLR). Recent investigations in humans were conducted to understand how the photoreceptor signals are combined to drive the pupil light reflex. This review is about the physiological processes that govern the pupil in humans. In particular, how cone-opsins, rhodopsin, and melanopsin photoreception contribute to governing the PLR. We also summarize investigations on the assessment of the PLR in clinical settings.