Single-step synthesis of 4-phenyl and 3,4-dihydro-4-phenyl coumarins using a recyclable Preyssler heteropolyacid catalyst under solvent-free reaction conditions
4-Phenyl and 3,4-dihydro-4-phenylcoumarins were prepared by direct esterification of phenols with phenylpropiolic and cinnamic acids, respectively, using a compound with Preyssler structure (H14P5NaW30O110) (PA) as heterogeneous catalyst under solvent-free reaction conditions, at 130 C, in a short r...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2015 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/6370 |
| Acceso en línea: | http://hdl.handle.net/11336/6370 |
| Access Level: | acceso abierto |
| Palabra clave: | 4-Phenylcoumarins 4-Phenyl-3 4-Dihydrocoumarins Preyssler Catalyst Solvent-Free Reaction Conditions https://purl.org/becyt/ford/2.4 https://purl.org/becyt/ford/2 https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| Sumario: | 4-Phenyl and 3,4-dihydro-4-phenylcoumarins were prepared by direct esterification of phenols with phenylpropiolic and cinnamic acids, respectively, using a compound with Preyssler structure (H14P5NaW30O110) (PA) as heterogeneous catalyst under solvent-free reaction conditions, at 130 C, in a short reaction time (2 h). Underthese conditions, very good yields (11 examples: 61 %–90 %), free of secondary products, were obtained. The catalyst is recyclable, nontoxic, neither air nor moisture sensitive, and easy to handle. The described methodology is a clean and useful alternative to synthesize oxygenated heterocycles based on a coumarin skeleton. |
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