Regulation of transcription factors by Tumor-Specific MAGE proteins
The tumor specific melanoma antigen gene (MAGE-I) family was initially considered promising and selective targets for immunotherapy. Currently, their functional characterization points to a role in transcription regulation. In this article we focus on MAGE-A proteins as regulators of transcription f...
| Authors: | , , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2015 |
| Country: | Argentina |
| Institution: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repository: | CONICET Digital (CONICET) |
| Language: | English |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/182728 |
| Online Access: | http://hdl.handle.net/11336/182728 |
| Access Level: | Open access |
| Keyword: | MAGE CANCER TRANSCRIPCTION FACTORS PROLIFERATION https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| Summary: | The tumor specific melanoma antigen gene (MAGE-I) family was initially considered promising and selective targets for immunotherapy. Currently, their functional characterization points to a role in transcription regulation. In this article we focus on MAGE-A proteins as regulators of transcription factors involved in different cancer-related pathways and how this regulation could contribute to tumorigenesis. |
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