Histamine modulates γδ-T lymphocyte migration and cytotoxicity, via Gi and Gs protein-coupled signalling pathways

The biogenic amine, histamine plays a pathophysiological regulatory role in cellular processes of a variety of immune cells. This work analyses the actions of histamine on γδ-T lymphocytes, isolated from human peripheral blood, which are critically involved in immunological surveillance of tumours

Detalles Bibliográficos
Autores: Truta Feles, K., Lagadari, Mariana, Lehmann, K., Berod, L., Cubillos, S., Piehler, S., Herouy, Y., Barz, D., Kamradt, T., Maghazachi, A. A., Norgauer, J.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/14684
Acceso en línea:http://hdl.handle.net/11336/14684
Access Level:acceso abierto
Palabra clave:Histamine
Gd T Lymphocytes
Migration
Cytotoxicity
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
Descripción
Sumario:The biogenic amine, histamine plays a pathophysiological regulatory role in cellular processes of a variety of immune cells. This work analyses the actions of histamine on γδ-T lymphocytes, isolated from human peripheral blood, which are critically involved in immunological surveillance of tumours