New perspectives in melatonin uses
This review summarizes the metabolism, secretion, regulation and sites of action of melatonin. An updated description of the melatonin receptors, including their signal transduction mechanisms, distribution and characterization of receptor genes, is given. Special emphasis is focused on the clinical...
| Autores: | , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/133937 |
| Acceso en línea: | http://hdl.handle.net/11336/133937 |
| Access Level: | acceso abierto |
| Palabra clave: | ANTIOXIDANT PROPERTIES CANCER CENTRAL NERVOUS SYSTEM GASTROINTESTINAL TRACT MELATONIN METABOLISM MELATONIN RECEPTORS https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
| Sumario: | This review summarizes the metabolism, secretion, regulation and sites of action of melatonin. An updated description of the melatonin receptors, including their signal transduction mechanisms, distribution and characterization of receptor genes, is given. Special emphasis is focused on the clinical aspects and potential uses of melatonin in the sleep-wake rhythms, in the immune function, in cancer therapy, in neuroprotection against oxidative damage and antioxidant activities in different tissues. Finally, combined effects of melatonin with other drugs are discussed. © 2012 Elsevier Ltd. All rights reserved. |
|---|