Elephantopus-type sesquiterpene lactones from a Vernonanthura species, Vernonanthura nebularum

Aerial parts of Vernonanthura nebularum, an Argentine endemic whose occurrence is limited to a small area in northwestern Argentina, afforded seven new sesquiterpene lactones of a type characteristic of some Elephantopodiinae rather than Vernonanthura of Vernoniinae. Structures were elucidated by hi...

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Detalles Bibliográficos
Autores: Pollora, Genaro Cesar, Bardon, Alicia del Valle, Catalan, Cesar Atilio Nazareno, Gedris, Thomas E., Herz, Werner
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/115084
Acceso en línea:http://hdl.handle.net/11336/115084
Access Level:acceso abierto
Palabra clave:SESQUITERPENE LACTONES
VERNONANTHURA NEBULARUM
VERNONIINAE
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:Aerial parts of Vernonanthura nebularum, an Argentine endemic whose occurrence is limited to a small area in northwestern Argentina, afforded seven new sesquiterpene lactones of a type characteristic of some Elephantopodiinae rather than Vernonanthura of Vernoniinae. Structures were elucidated by high field 1 H-NMR spectrometry. In revising the generic and subtribal classification of neotropical Vernoniae H. Robinson (Robinson, 1994, 1999) established the new genus Vernonanthura as a segregate from Vernonia sensu stricto (Robinson, 1992) and subsequently included within it (Robinson, 1995) Vernonia nebularum Cabrera as Vernonanthura nebularum (Cabr.) H. Robinson (Cabrera, 1978). Earlier chemical studies of Vernonanthura species, frequently under the old Vernonia binomials (Robinson, 1999), had resulted in the isolation of a variety of flavonoids and sesquiterpene lactones similar to or identical with such compounds found in other Vernonieae (Wagner et al., 1972; Mabry et al., 1975; Bohlmann and Zdero, 1977, 1988; Maldonado et al., 1980; Bohlmann et al., 1981a,b, 1983; Jakupovic et al., 1986, 1987a,b; Catala´n et al., 1986, 1988; Stutts, 1988; Bardo´n et al., 1988, 1992; Budesinsky et al., 1994; Borkosky et al., 1997; Bazon et al., 1997; Kotowicz et al., 1998), while in one instance the occurrence of pimarane and kaurane derivatives was reported (Borkosky et al., 1995). We now describe our chemical study of Vernonanthura nebularum, an Argentine endemic whose occurrence is limited to the Sierra de Calilegua within Jujuy province, Argentina.