Africane-type sesquiterpenoids from the Argentine liverwort porella swartziana and their antibacterial activity

Seven africanes (1, 2a, b, 3-6), two of them new (1, 2a) three secoafricanes (7, 9), one of them new (7), and two norsecoafricanes (10, 11a), one of them new (10), all of them swartzianin-type, have been isolated from an Argentine collection of the endemic liverwort Porella swartziana. The structure...

Full description

Bibliographic Details
Authors: Bovi Mitre, Graciela, Kamiya, Norma Inés, Bardon, Alicia del Valle, Yoshinori Asakawa
Format: article
Status:Published version
Publication Date:2004
Country:Argentina
Institution:Consejo Nacional de Investigaciones Científicas y Técnicas
Repository:CONICET Digital (CONICET)
Language:English
OAI Identifier:oai:ri.conicet.gov.ar:11336/105640
Online Access:http://hdl.handle.net/11336/105640
Access Level:Open access
Keyword:SESQUITERPENOIDS
LIVERWORT
PORELLA
ANTIBACTERIAL
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Description
Summary:Seven africanes (1, 2a, b, 3-6), two of them new (1, 2a) three secoafricanes (7, 9), one of them new (7), and two norsecoafricanes (10, 11a), one of them new (10), all of them swartzianin-type, have been isolated from an Argentine collection of the endemic liverwort Porella swartziana. The structures of the new compounds were established by extensive 1D and 2D NMR spectroscopic data. Absolute configurations of compounds 2a, 2b and 10 were derived on the basis of CD spectra. The compounds were tested for activity against a variety of microbes, but none were found to exhibit significant antibacterial activity.