Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?

Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease whose prevalence has reached global epidemic proportions, not only in adults but also in children. From a clinical point of view, NAFLD stems a myriad of challenges to physicians, researchers and patients. In this study, we r...

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Detalhes bibliográficos
Autores: Sookoian, Silvia Cristina, Pirola, Carlos José
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/20550
Acesso em linha:http://hdl.handle.net/11336/20550
Access Level:acceso abierto
Palavra-chave:Fatty Liver
Personalized Medicine
Risk Prediction
Genetics
Insulin Resistance
Alt
Ast
Cad
Metabolic Syndrome
Nafld
Nash
Pnpla3
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
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oai_identifier_str oai:ri.conicet.gov.ar:11336/20550
network_acronym_str AR
network_name_str Argentina
repository_id_str
spelling Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?Sookoian, Silvia CristinaPirola, Carlos JoséFatty LiverPersonalized MedicineRisk PredictionGeneticsInsulin ResistanceAltAstCadMetabolic SyndromeNafldNashPnpla3https://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease whose prevalence has reached global epidemic proportions, not only in adults but also in children. From a clinical point of view, NAFLD stems a myriad of challenges to physicians, researchers and patients. In this study, we revise the current knowledge and recent insights on NAFLD pathogenesis and diagnosis in the context of a personalized perspective with special focus on the following issues: noninvasive biomarkers for the evaluation of disease severity and progression, lifestyle-related patients’ recommendations, risk prediction of disease by genetic testing, management of NAFLD-associated comorbidities and patient-oriented therapeutic intervention strategies.Fil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Pirola, Carlos José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFuture Medicine2014-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/20550Sookoian, Silvia Cristina; Pirola, Carlos José; Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?; Future Medicine; Personalized Medicine; 11; 8; 11-2014; 735-7431741-0541CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.futuremedicine.com/doi/abs/10.2217/pme.14.44info:eu-repo/semantics/altIdentifier/doi/10.2217/pme.14.44info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T14:21:45Zoai:ri.conicet.gov.ar:11336/20550instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 14:21:45.747CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?
title Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?
spellingShingle Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?
Sookoian, Silvia Cristina
Fatty Liver
Personalized Medicine
Risk Prediction
Genetics
Insulin Resistance
Alt
Ast
Cad
Metabolic Syndrome
Nafld
Nash
Pnpla3
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
title_short Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?
title_full Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?
title_fullStr Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?
title_full_unstemmed Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?
title_sort Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?
dc.creator.none.fl_str_mv Sookoian, Silvia Cristina
Pirola, Carlos José
author Sookoian, Silvia Cristina
author_facet Sookoian, Silvia Cristina
Pirola, Carlos José
author_role author
author2 Pirola, Carlos José
author2_role author
dc.subject.none.fl_str_mv Fatty Liver
Personalized Medicine
Risk Prediction
Genetics
Insulin Resistance
Alt
Ast
Cad
Metabolic Syndrome
Nafld
Nash
Pnpla3
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
topic Fatty Liver
Personalized Medicine
Risk Prediction
Genetics
Insulin Resistance
Alt
Ast
Cad
Metabolic Syndrome
Nafld
Nash
Pnpla3
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
description Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease whose prevalence has reached global epidemic proportions, not only in adults but also in children. From a clinical point of view, NAFLD stems a myriad of challenges to physicians, researchers and patients. In this study, we revise the current knowledge and recent insights on NAFLD pathogenesis and diagnosis in the context of a personalized perspective with special focus on the following issues: noninvasive biomarkers for the evaluation of disease severity and progression, lifestyle-related patients’ recommendations, risk prediction of disease by genetic testing, management of NAFLD-associated comorbidities and patient-oriented therapeutic intervention strategies.
publishDate 2014
dc.date.none.fl_str_mv 2014-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/20550
Sookoian, Silvia Cristina; Pirola, Carlos José; Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?; Future Medicine; Personalized Medicine; 11; 8; 11-2014; 735-743
1741-0541
CONICET Digital
CONICET
url http://hdl.handle.net/11336/20550
identifier_str_mv Sookoian, Silvia Cristina; Pirola, Carlos José; Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?; Future Medicine; Personalized Medicine; 11; 8; 11-2014; 735-743
1741-0541
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.futuremedicine.com/doi/abs/10.2217/pme.14.44
info:eu-repo/semantics/altIdentifier/doi/10.2217/pme.14.44
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Future Medicine
publisher.none.fl_str_mv Future Medicine
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1799196288681508864
score 15.811543

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