Acetylcholine contributes to control the physiological inflammatory response during the peri-implantation period

Maternal antigen-presenting cells attracted to the pregnant uterus interact with trophoblast cells and modulate their functional profile to favour immunosuppressant responses. Non-neuronal cholinergic system is expressed in human cytotrophoblast cells and in immune cells with homeostatic regulatory...

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Detalles Bibliográficos
Autores: Paparini, Daniel Esteban, Gori, María Soledad, Grasso, Esteban Nicolas, Scordo, W., Calo, G., Perez Leiros, Claudia, Ramhorst, Rosanna Elizabeth, Salamone, Gabriela Veronica
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/42758
Acceso en línea:http://hdl.handle.net/11336/42758
Access Level:acceso abierto
Palabra clave:Acetylcholine
peri-implantation period
dendritic cells
non-neuronal acetylcholine
embryo implantation
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
Descripción
Sumario:Maternal antigen-presenting cells attracted to the pregnant uterus interact with trophoblast cells and modulate their functional profile to favour immunosuppressant responses. Non-neuronal cholinergic system is expressed in human cytotrophoblast cells and in immune cells with homeostatic regulatory functions. The aim of this work was to evaluate whether non-neuronal acetylcholine conditions maternal monocyte and DC migration and activation profiles.

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