Polymerase-functionalized hierarchical mesoporous titania thin films: Towards a nanoreactor platform for DNA amplification

Nucleic acids are essential in life, as they control the functioning of the cells and carry the genetic information. DNA manipulation has become one of the most active research areas of current science. As a consequence, the development of advanced platforms able to interact with DNA is blooming. [1...

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Detalhes bibliográficos
Autores: Bellino, Martin Gonzalo, Tropper, Ivanna, Duran, Hebe Alicia, Regazzoni, Alberto Ernesto, Soler Illia, Galo Juan de Avila Arturo
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/99240
Acesso em linha:http://hdl.handle.net/11336/99240
Access Level:acceso abierto
Palavra-chave:DNA
HIERARCHICAL FILMS
MESOPOROUS THIN FILMS
NANOBIOTECHNOLOGY
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descrição
Resumo:Nucleic acids are essential in life, as they control the functioning of the cells and carry the genetic information. DNA manipulation has become one of the most active research areas of current science. As a consequence, the development of advanced platforms able to interact with DNA is blooming. [1] Integration of novel nanomaterials with advanced molecular biology techniques constitutes one of the main targets of nanobiotechnology. Here we report that polymerase-containing titania thin films of appropriate hierarchical nanoporous architecture are capable of performing DNA amplification.