New Scenarios for Brucella suis and Brucella melitensis

Purpose of Review We pretend to highlight the most important advances reached in the last few years in the biology of<em>Brucella suis</em>and<em>Brucella melitensis</em>and focus attention on new tools for the comprehension, prevention and control of these zoonotic agents. R...

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Detalhes bibliográficos
Autores: Samartino, Luis, Arregui, Matías, Martino, Pablo Eduardo
Tipo de documento: artigo
Estado:Versión enviada para evaluación y publicación
Data de publicação:2017
País:Argentina
Recursos:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
Repositório:CIC Digital (CICBA)
Idioma:inglês
OAI Identifier:oai:digital.cic.gba.gob.ar:11746/5940
Acesso em linha:https://digital.cic.gba.gob.ar/handle/11746/5940
Access Level:Acceso aberto
Palavra-chave:Ciencias Veterinarias
Brucella suis
Brucella melitensis
pathogenesis
vaccines
Descrição
Resumo:Purpose of Review We pretend to highlight the most important advances reached in the last few years in the biology of<em>Brucella suis</em>and<em>Brucella melitensis</em>and focus attention on new tools for the comprehension, prevention and control of these zoonotic agents. Recent Findings Important progress lately done in the field of pathogenesis is presented here. This involves current studies on proteins involved in the survival and antigenic structure of<em>Brucella</em>, as well as the findings of how<em>Brucella</em>has achieved modifications in order to adapt, replicate, survive and modulate the host´s immune system, improve the knowledge of the performance of these bacteria. Summary Consequently, better approaches for vaccinology and diagnostic techniques are developed. Relevant epidemiological issues based on changes in the highly conserved genome of these bacteria will be valuable tools to describe outbreaks and disease status, along with risk factors that would otherwise be difficult to analyze.