Review of biosensing with whispering-gallery mode lasers

Lasers are the pillars of modern optics and sensing. Microlasers based on whispering-gallery modes (WGMs) are miniature in size and have excellent lasing characteristics suitable for biosensing. WGM lasers have been used for label-free detection of single virus particles, detection of molecular elec...

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Detalles Bibliográficos
Autores: Toropov, Nikita A., Cabello, Gema, Serrano, Mariana Paula, Gutha, Rithvik R., Rafti, Matías, Vollmer, Frank
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Argentina
Institución:Universidad Nacional de La Plata
Repositorio:SEDICI (UNLP)
Idioma:inglés
OAI Identifier:oai:sedici.unlp.edu.ar:10915/123771
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/123771
Access Level:acceso abierto
Palabra clave:Ciencias Exactas
Física
Lasers
Whispering-gallery modes
Sensing mechanisms
Descripción
Sumario:Lasers are the pillars of modern optics and sensing. Microlasers based on whispering-gallery modes (WGMs) are miniature in size and have excellent lasing characteristics suitable for biosensing. WGM lasers have been used for label-free detection of single virus particles, detection of molecular electrostatic changes at biointerfaces, and barcode-type live-cell tagging and tracking. The most recent advances in biosensing with WGM microlasers are described in this review. We cover the basic concepts of WGM resonators, the integration of gain media into various active WGM sensors and devices, and the cutting-edge advances in photonic devices for micro- and nanoprobing of biological samples that can be integrated with WGM lasers.