Going Forward with Lymphocytes Immunotherapies for Treatment of Unexplained Recurrent Spontaneous Abortion

Recurrent spontaneous abortion (RSA), defined as the occurrence of two or more consecutive miscarriages at less than 22-weeks of gestation [1], is one of the major pregnancy disorders and affects up to 5% of couples of reproductive ages. Although genetic factors, hormonal diseases, anatomical anomal...

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Detalhes bibliográficos
Autores: Arana, Eloisa, Fernandez, Pablo Mariano
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2019
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositório:CONICET Digital (CONICET)
Idioma:inglês
OAI Identifier:oai:ri.conicet.gov.ar:11336/110693
Acesso em linha:http://hdl.handle.net/11336/110693
Access Level:Acceso aberto
Palavra-chave:ABORTION
IMMUNITY
IMMUNOTHERAPY
TREATMENT
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
Descrição
Resumo:Recurrent spontaneous abortion (RSA), defined as the occurrence of two or more consecutive miscarriages at less than 22-weeks of gestation [1], is one of the major pregnancy disorders and affects up to 5% of couples of reproductive ages. Although genetic factors, hormonal diseases, anatomical anomalies and antiphospholipid syndrome have been linked with RSA [2,3], 50% of cases still remain unexplained and generate growing interest to unveil potential involved mechanism, particularly for those that imply immunological pathways