Pathogenesis and immune response in Brucella infection acquired by the respiratory route

Brucella infection is frequently acquired through the respiratory route. The pathogen disseminates systemically from the lungs to infect peripheral organs. In this review we summarize the existing data on the pathogenesis of inhalational Brucella infection, the pulmonary immune response to the patho...

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Detalhes bibliográficos
Autores: Ferrero, Mariana Cristina, Alonso Paiva, Iván Mathias, Muñoz González, Florencia, Baldi, Pablo Cesar
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/141670
Acesso em linha:http://hdl.handle.net/11336/141670
Access Level:acceso abierto
Palavra-chave:BRUCELLA
IMMUNE RESPONSE
INHALATIONAL INFECTION
PATHOGENESIS
VACCINES
https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
Descrição
Resumo:Brucella infection is frequently acquired through the respiratory route. The pathogen disseminates systemically from the lungs to infect peripheral organs. In this review we summarize the existing data on the pathogenesis of inhalational Brucella infection, the pulmonary immune response to the pathogen, and potential strategies for inducing protective lung immunity.

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