Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1
A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to t...
| Autores: | , , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2008 |
| País: | Argentina |
| Institución: | Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán" |
| Repositorio: | Sistema de Gestión del Conocimiento ANLIS MALBRÁN |
| Idioma: | inglés |
| OAI Identifier: | oai:sgc.anlis.gob.ar:123456789/243 |
| Acceso en línea: | http://sgc.anlis.gob.ar/handle/123456789/243 http://www.ajtmh.org/content/79/1/89.full.pdf+html |
| Access Level: | acceso abierto |
| Palabra clave: | Equinococosis Echinococcus granulosus Zoonosis Enfermedades de las Ovejas Humanos Reacción en Cadena de la Polimerasa Genotipo Complejo IV de Transporte de Electrones ADN Mitocondrial ADN de Helmintos Perú |
| Sumario: | A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs. |
|---|