The SARS-CoV-2 mutation landscape is shaped before replication starts

Mutation landscapes and signatures have been thoroughly studied in SARS-CoV-2. Here, we analyse those patterns and link their changes to the viral replication niche. Surprisingly, those patterns look to be also modified after vaccination. Hence, by deductive reasoning we identify the steps of the co...

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Detalles Bibliográficos
Autores: Masone, Diego Fernando, Alvarez, Maria Soledad, Polo Ilacqua, Luis Mariano
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/204696
Acceso en línea:http://hdl.handle.net/11336/204696
Access Level:acceso abierto
Palabra clave:RELICATION NICHE
VACCINATION
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
Descripción
Sumario:Mutation landscapes and signatures have been thoroughly studied in SARS-CoV-2. Here, we analyse those patterns and link their changes to the viral replication niche. Surprisingly, those patterns look to be also modified after vaccination. Hence, by deductive reasoning we identify the steps of the coronavirus infection cycle in which those mutations initiate.