Clotting effect of two coca leaf varieties on albino rat blood samples

This investigation evaluates the clotting effect of extracts of two varieties of coca leaves: Erytrhoxylum coca var. Coca and novogranatense Erytrhoxylum var. Truxillense. The aim of the study was to determine the shortest time of clotting of the blood samples of the albin rats. 34 males and female...

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Bibliographic Details
Authors: Díaz Soriano, Ana María, Pérez Vargas, Luis Fernando, Castro Rodríguez, Antonia, Chein Villacampa, Sylvia, Sánchez Huamaní, Juan, Tenorio Estrada, Janet, Vilchez Quintana, Ernesto
Format: article
Status:Published version
Publication Date:2007
Country:Perú
Institution:Universidad Nacional Mayor de San Marcos
Repository:Revistas - Universidad Nacional Mayor de San Marcos
Language:Spanish
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/2891
Online Access:https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/2891
Access Level:Open access
Keyword:Coca leaf
clotting time
Erythroxylum novogranatense var
Truxillense
Erytrhoxylum coca lam var. Coca.
Hoja de coca
tiempo de coagulación
Variedades de hoja de coca.
Description
Summary:This investigation evaluates the clotting effect of extracts of two varieties of coca leaves: Erytrhoxylum coca var. Coca and novogranatense Erytrhoxylum var. Truxillense. The aim of the study was to determine the shortest time of clotting of the blood samples of the albin rats. 34 males and female rats were selected to have 3 ml. of blood of each one. The blood samples were distributed in three probes containing: 0,06 ml. of physiological serum (control group), 0,06 ml. extract of E. coca lam var. coca (coca group), and 0,06 ml. of extract E. novogranatense var. truxillense (truxillense group). The clotting time for the control group was of 1,42 (±0.31) min, coca group: 1,38 (±0.26) min, truxillense group 1,83 (±0.55) min. The Anova analysis of the results showed significant differences between groups (p<0.01). The coca group showed the shortest clotting time of all groups. The truxillense group showed an inhibiting clotting effect compared to control group.