Thoracoabdominal normothermic regional perfusion-approaches to arch vessels and options of cannulation allowing donation after circulatory death multi-organ perfusion and procurement
Since 2015, the use of hearts from controlled donation after circulatory death (DCD) donors for transplantation has steadily increased, with short-term outcomes shown to be comparable to those from donation after brainstem death (DBD) (1). Thoracoabdominal normothermic regional perfusion (TA-NRP) ha...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universidad de Cantabria (UC) |
| Repositorio: | UCrea Repositorio Abierto de la Universidad de Cantabria |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.unican.es:10902/36674 |
| Acceso en línea: | https://hdl.handle.net/10902/36674 |
| Access Level: | acceso abierto |
| Palabra clave: | Thoracoabdominal normothermic regional perfusion (TA-NRP) Donation after circulatory death heart transplantation (DCD heart transplantation) Donor heart procurement |
| Sumario: | Since 2015, the use of hearts from controlled donation after circulatory death (DCD) donors for transplantation has steadily increased, with short-term outcomes shown to be comparable to those from donation after brainstem death (DBD) (1). Thoracoabdominal normothermic regional perfusion (TA-NRP) has emerged as an effective strategy to rapidly restore perfusion to and optimise the quality of thoracoabdominal organs in situ after circulatory death is confirmed (2). However, implementation of TA-NRP varies between countries and institutions due to differences in ethical considerations, regulatory policies, and legal frameworks surrounding DCD. A primary ethical concern focuses on the potential for blood flow to return to the brain during TA-NRP (3). This paper and associated video demonstrate the three most common approaches to arch vessels and cannulation for TA-NRP, that are adopted by the teams in the United States of America (USA), Spain, and the United Kingdom (UK) (4). |
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