Image_3_Chloroquine-induced DNA damage synergizes with DNA repair inhibitors causing cancer cell death.tif [Dataset]

[Background]: Cancer is a global health problem accounting for nearly one in six deaths worldwide. Conventional treatments together with new therapies have increased survival to this devastating disease. However, the persistent challenges of treatment resistance and the limited therapeutic arsenal a...

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Detalles Bibliográficos
Autores: Iglesias-Corral, Diego, García-Valles, Paula, Arroyo-Garrapucho, Nuria, Bueno-Martínez, Elena, Ovejero-Sánchez, María
Tipo de recurso: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/364718
Acceso en línea:http://hdl.handle.net/10261/364718
Access Level:acceso abierto
Palabra clave:Breast cancer
Colorectal cancer
Head and neck cancer
Glioblastoma
Chloroquine
DNA repair inhibitors
Drug combination
Descripción
Sumario:[Background]: Cancer is a global health problem accounting for nearly one in six deaths worldwide. Conventional treatments together with new therapies have increased survival to this devastating disease. However, the persistent challenges of treatment resistance and the limited therapeutic arsenal available for specific cancer types still make research in new therapeutic strategies an urgent need.