Percutaneous mitral valve repair

Background and aim: Recent randomized data comparing percutaneous mitral valve repair (PMVR) versus optimal medical treatment in patients with functional MR (FMR) seemed to highlight the importance of the learning curve not only for procedural outcomes but also for patient selection. The aim of the...

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Autores: Freixa, Xavier|||0000-0002-3203-9060, Estevez-Loureiro, Rodrigo|||0000-0001-5841-5514, Carrasco-Chinchilla, Fernando|||0000-0003-0549-3214, Millán, Xavier|||0000-0001-6519-4190, Amat-Santos, Ignacio J.|||0000-0002-2311-4129, Regueiro, Ander|||0000-0001-5201-447X, Nombela-Franco, Luís|||0000-0003-3438-8907, Pascual, Isaac|||0000-0001-5433-1364, Cid-Álvarez, Belén, López Mínguez, José Ramón|||0000-0002-0657-4457, Hernández-Antolín, Rosa Ana, Cruz-González, Ignacio|||0000-0001-9742-6072, Andraka, Leire, Goicolea, Javier|||0000-0003-1289-2328, Ruíz-Quevedo, Valeriano, Diez-Gil, José Luís|||0000-0001-9921-8023, Berenguer, Alberto, Baz, José Antonio, Pan Álvarez-Ossorio, Manuel|||0000-0003-0356-9051, Benito-González, Tomás|||0000-0002-8428-9248, Alonso Briales, Juan H., Li, Chi Hion|||0000-0001-7556-3711, Sanchis, Laura|||0000-0003-2516-8953, Serrador Frutos, Ana María|||0009-0009-9037-1019, Jiménez-Quevedo, Pilar, Avanzas, Pablo|||0000-0002-4958-6108, Salido, Luisa, Fernández-Vázquez, Felipe|||0000-0001-7187-1290, Hernández-García, José Maria, Arzamendi, Dabit|||0000-0001-7543-5867
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:269925
Acceso en línea:https://ddd.uab.cat/record/269925
https://dx.doi.org/urn:doi:10.3390/jcm10040734
Access Level:acceso abierto
Palabra clave:Transcatheter mitral valve repair
Mitral regurgitation
MitraClip
Descripción
Sumario:Background and aim: Recent randomized data comparing percutaneous mitral valve repair (PMVR) versus optimal medical treatment in patients with functional MR (FMR) seemed to highlight the importance of the learning curve not only for procedural outcomes but also for patient selection. The aim of the study was to compare a contemporary series of patients undergoing PMVR using a second-generation Mitraclip device (Mitraclip NT) with previous cohorts treated with a first-generation system. Methods: This multicenter study collected individual data from 18 centers between 2012 and 2017. The cohort was divided into three groups according to the use of the first-generation Mitraclip during the first (control-1) or second half (control-2) or the Mitraclip NT sys-tem. Results: A total of 545 consecutive patients were included in the study. Among all, 182 (33.3%), 183 (33.3%), and 180 (33.3%) patients underwent mitral repair in the control-1, control-2, and NT cohorts, respectively. Procedural success was achieved in 93.3% of patients without differences between groups. Major adverse events did not statistically differ among groups, but there was a higher rate of pericardial effusion in the control-1 group (4.3%, 0.6%, and 2.6%, respectively; p = 0.025). The composite endpoint of death, surgery, and admission for congestive heart failure (CHF) at 12 months was lower in the NT group (23.5% in control-1, 22.5% in control-2, and 8.3% in the NT group; p = 0.032). Conclusions: The present paper shows that contemporary clinical outcomes of patients undergoing PMVR with the Mitraclip system have improved over time.

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