Structural and molecular mechanisms af ATP-dependent DNA transposition using IS21 as a model system
Transposition encompasses a range of biological processes in wich DNA segment can move between different genomic locations using enzymes called transposases. This ubiquitous process can cause mutations in the host genome, drive chromosomal rearrangements and the dissemination of drug-resistance gene...
| Autor: | |
|---|---|
| Formato: | tesis doctoral |
| Fecha de publicación: | 2024 |
| País: | España |
| Recursos: | Universidad Complutense de Madrid (UCM) |
| Repositorio: | Docta Complutense |
| Idioma: | inglés |
| OAI Identifier: | oai:docta.ucm.es:20.500.14352/110454 |
| Acesso em linha: | https://hdl.handle.net/20.500.14352/110454 |
| Access Level: | acceso abierto |
| Palavra-chave: | 577.1(043.2) Bioquímica Biochemistry Bioquímica (Química) 2302 Bioquímica |
| Resumo: | Transposition encompasses a range of biological processes in wich DNA segment can move between different genomic locations using enzymes called transposases. This ubiquitous process can cause mutations in the host genome, drive chromosomal rearrangements and the dissemination of drug-resistance genes and toxins. Transposition must be carefully regulated to minimize harm to the host and prevent deteriorous DNA beraks... |
|---|