The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury

Spinal cord injury (SCI) is a devastating condition that impacts multiple organ systems. Neurogenic bowel dysfunction (NBD) frequently occurs after a SCI leading to reduced sensation of bowel fullness and bowel movement often leading to constipation or fecal incontinence. Spinal Neuromodulation has...

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Detalles Bibliográficos
Autores: Kreydin, Evgeniy|||0000-0001-8207-3809, Zhong, Hui, Lavrov, Igor, Edgerton, Victor|||0000-0001-6534-1875, Gad, Parag|||0000-0001-8352-7614
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:258964
Acceso en línea:https://ddd.uab.cat/record/258964
https://dx.doi.org/urn:doi:10.3389/fnins.2022.816106
Access Level:acceso abierto
Palabra clave:Non-invasive spinal cord stimulation
Spinal cord injury
Stroke
Multiple sclerosis
Neurogenic bladder
Overactive bladder urodynamics
Descripción
Sumario:Spinal cord injury (SCI) is a devastating condition that impacts multiple organ systems. Neurogenic bowel dysfunction (NBD) frequently occurs after a SCI leading to reduced sensation of bowel fullness and bowel movement often leading to constipation or fecal incontinence. Spinal Neuromodulation has been proven to be a successful modality to improve sensorimotor and autonomic function in patients with spinal cord injuries. The pilot data presented here represents the first demonstration of using spinal neuromodulation to activate the anorectal regions of patients with spinal cord injuries and the acute and chronic effects of stimulation. We observed that spinal stimulation induces contractions as well as changes in sensation and pressure profiles along the length of the anorectal region. In addition, we present a case report of a patient with a SCI and the beneficial effect of spinal neuromodulation on the patient's bowel program.