Exploring genomic regions regulating the liver transcriptome and energy homeostasis in pigs

The analysis of the transcriptome can enhance the understanding of the link between genetic variants and phenotypes of interest. In this study, eQTL mapping, ASE analysis and aseQTL mapping allowed the identification of regulatory mechanisms of the hepatic transcriptome in a commercial population of...

ver descrição completa

Detalhes bibliográficos
Autores: Llobet-Cabau, Ferran, Liu, Junhui, Jové-Juncà, Teodor, Castelló Farré, Anna, Quintanilla, Raquel, Sanchez, Armand, Ballester Devis, Maria, Folch, Josep M
Formato: conjunto de datos
Fecha de publicación:2026
País:España
Recursos:Consorci de Serveis Universitaris de Catalunya (CSUC)
Repositorio:CORA.Repositori de Dades de Recerca
OAI Identifier:oai:dnet:cora.rdr____::071bfba23270e0b3b074c3661ae69e48
Acesso em linha:https://doi.org/10.34810/DATA3086
Access Level:acceso abierto
Palavra-chave:Agricultural Sciences
RNA-Seq
eGWAS
eQTL
Allele-specific expression
aseQTL
Descrição
Resumo:The analysis of the transcriptome can enhance the understanding of the link between genetic variants and phenotypes of interest. In this study, eQTL mapping, ASE analysis and aseQTL mapping allowed the identification of regulatory mechanisms of the hepatic transcriptome in a commercial population of 310 Duroc pigs. Integration with previously generated QTL data for fatty acid composition traits allowed the identification of putative molecular mechanisms and shared causal variants. This repository contains Supplementary Table S4 (aseQTLs identified in this study) and Supplementary Table S5 (All SNPs reported in the results of colocalization analysis between eQTL and QTL regions).